Funding Agency:
MacArthur Foundation, John D. and Catherine T.

100&Change is a global competition for a proposal that promises measureable progress toward solving a critical social challenge. The MacArthur Foundation will award one $100 million grant to help make that solution a reality. The competition is open to organizations working in any field, anywhere in the world. Competitive proposals will address a significant problem and provide a solution that is impactful, evidence-based, feasible, and durable. Projects must be ready to scale.

Top scoring applicants will receive domain-specific technical reviews in which proposals will be assigned to a technical reviewer with expertise in the field of the proposed project. MacArthur will seek to generate increased recognition and support for high-impact ideas designated as “Bold Solutions,” by featuring them in their online database of the strongest proposals. Ten semi-finalists will work with an expert team to strengthen their proposals, present a preliminary plan for monitoring and evaluation and learning, and show authentic engagement with communities of interest before submitting revised project plans. Selection of the final award recipient rests with MacArthur’s board.

There is no restriction on the number of applicants from a single institution; however, through an internal competition, Duke intends to select one project to receive internal assistance with proposal development and video production, in order to have the strongest submission possible.  Internal semi-finalists may be asked to make a brief in-person pitch to the selection committee in April.

Prospective applicants should take into consideration that a full proposal submitted to MacArthur requires a strong project leader, many hours of preparation, and the creation of a promotional video. This is an extremely competitive program with only one grant awarded and, for the 2019 competition, there are no semifinalist awards. Prospective applicants are encouraged to review the 2017 awards, including semifinalist Rice University, to understand the scope of work and impact that MacArthur is seeking: https://www.macfound.org/programs/100change/recipients/

Please contact vera.luck@duke.edu and Alexandra.de.havilland@duke.edu (Duke Office of Foundation Relations) with any questions.

Duke internal Deadline: April 8, 2019 COB

Deadline for Registration: July 16, 2019


Agency Website



Funding Type





Arts & Humanities
Community Outreach and Engagement
Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

Internal Nomination

Please submit the following information in a PDF using 12 point font and 1 inch margins.

  1. Organizational Readiness Tool

    1. Complete questions #3, 5, 6, and 7 from MacArthur’s Readiness Tool: https://www.macfound.org/media/files/100Change-Organization-Readiness-Tool.pdf. Submit your responses with your internal application. Scanned, hand-written notes on the Tool document are acceptable.
  2. Cover Page:

On a single page, please provide:

  1. Project Title
  2. Team Members: List lead PI (with contact information), key Duke team members, and any non-Duke partners 
  3. Project Description: Provide a short description of your project in one sentence.
  4. Executive Summary (one paragraph). Write an overview of your project that answers the following three questions: 1) What is a brief description of the problem that you are trying to solve?  2) How will you solve it?  3) How will your solution change the lives of the people you wish to serve, including historically marginalized people within that population?

3. Project Details:

Using no more than two pages total, please describe the following:

  • Problem Statement: Describe the specific challenges that your solution will address, using non-expert language. Who is impacted by the problem and do they recognize the problem as urgent? Why does the problem exist in the current environment? What are the most influential ways to effect the necessary change, and where are the leverage points where the smallest change can have the biggest impact?
  • Solution Overview: Using non-expert language, address the following questions: How does your solution meaningfully contribute to resolving the chosen problem?  How will you know you are making progress? Describe the impact your solution will have over a five-year period. Describe who will benefit from your solution and the benefits or outcomes of your solution.
  • Projected Impact: What evidence do you have, or why do you believe that the solution you propose will work?
  • Alignment with the United Nations Sustainable Development Goals: In one sentence list the SDGs, if any, that align with your solution. See here for reference: https://www.un.org/sustainabledevelopment/sustainable-development-goals/
  • Diversity, Equity, and Inclusion: Explain how you will ensure, or have ensured, that you solution will be inclusive. For example, how will it include or engage the community in which your project will take place (or has taken place) and also include historically marginalized populations?

Applicants will need to submit internal materials through My Research Proposal (select ILN access code). https://www.grantinterface.com/Common/LogOn.aspx?eqs=ApVvmgXCk2Uj7AzWyDEJKQ2

Instructions for creating an account (if needed) and submitting your materials: https://www.ctsi.duke.edu/myresearchproposal


Internal Deadline

April 8, 2019

External Deadline

August 6, 2019