2023 Cross-Species Studies of ASD — Request for Applications

Funding Agency:
Simons Foundation

Grants awarded through the Cross-Species Studies of ASD request for applications (RFA) are intended to support multi-disciplinary teams of PIs with expertise in both human and animal research to perform coordinated cross-species studies to advance our understanding of ASD-relevant behaviors and their underlying neurobiological mechanisms, with the potential for developing novel biomarkers or interventions.

Applicants may request a maximum of $400,000, inclusive of 20 percent indirect costs, for each year of funding over a period of two (2) to three (3) years.

The Cross-Species Studies of ASD RFA will support research on ASD-relevant behaviors and their underlying neurobiological mechanisms conducted in parallel across human and non-human animals. Because the focus is on translation across species, in addition to being relevant to ASD, the behaviors under study should be conserved across species and able to be measured objectively and quantitatively. Three domains SFARI recognizes as fitting these criteria include sensory function, motor function and sleep, although other behaviors will be considered if there is a strong argument that they meet these criteria.

Application Deadline: June 15, 2023

Agency Website

Eligibility Requirements

All applicants and key collaborators must hold a Ph.D., M.D. or equivalent degree and have a faculty position or the equivalent at a college, university, medical school or other research facility.

Principal investigators (PIs) who do not have substantial expertise with ASD participants should include a close collaborator with such expertise on their grant application (e.g., multi-PI application). For animal researchers interested in applying to this RFA who do not have an existing collaboration with someone who studies humans with ASD, please reach out to SFARI staff via sciencerfa@simonsfoundation.org; we may be able to help identify appropriate and interested potential collaborators.

SFARI recognizes the importance of diverse viewpoints for scientific advancement. As such, SFARI encourages the inclusion of researchers who span career stages and groups historically underrepresented in science.

Applications may be submitted by domestic and foreign nonprofit organizations; public and private institutions, such as colleges, universities, hospitals, laboratories and units of state and local government; and eligible agencies of the federal government. There are no citizenship or country requirements.



Amount Description

Applicants may request a maximum of $400,000, inclusive of 20 percent indirect costs, for each year of funding over a period of two (2) to three (3) years. Allowable Indirect costs to the primary institution for subcontracts are not included in the total budget threshold (see grant policies). We encourage investigators to take advantage of the flexibility in budget and duration, tailoring the scope of the award as appropriate for their specific aims. As with all SFARI-funded projects, it is at Simons Foundation’s discretion to modify final budgets as needed.

Funding Type



Women and minorities encouraged


Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science

External Deadline

June 15, 2023