Administrative Supplement for Research on Sex/Gender Influences (Admin Supp Clinical Trial Optional)

Funding Agency:
National Institutes of Health
The Office of Research on Women's Health (ORWH) announces the availability of administrative supplements to support research highlighting the impact of sex/gender influences in human health and illness, including basic, preclinical, clinical, translational, and behavioral studies. Of special interest are studies relevant to understanding the significance of biological sex on cells and tissue explants; comparative studies of male and female tissues, organ systems and physiological systems; sex-based comparisons of pathophysiology, biomarkers, gene expression, clinical presentation and prevention and treatment of diseases. The most robust experimental designs include consideration of both sex and gender; therefore, applications proposing to investigate the influence of both sex and gender factors are highly encouraged. The proposed research must address at least one of the five strategic goals of the new 2019-2023 Trans-NIH Strategic Plan for Women's Health Research"Advancing Science for the Health of Women".  

Application Due Date(s): February 20, 2019

PA-19-165 Expiration Date February 21, 2019

Agency Website

Eligibility Requirements

All organizations administering an eligible parent award may apply for a supplement under this announcement.

Individual(s) must hold an active grant or cooperative agreement, and the research proposed in the supplement must be accomplished within the competitive segment of the active award. Individuals are encouraged to work with their organizations to develop applications for support.

For supplements to parent awards that include multiple PDs/PIs, the supplement may be requested by any or all of the PDs/PIs (in accordance with the existing leadership plan) and submitted by the awardee institution of the parent award. Do not use this administrative supplement application to add, delete, or change the PDs/PIs listed on the parent award. Visit the Multiple Program Director/Principal Investigator Policy in the SF424 (R&R) Application Guide for more information.

Applicant organizations may submit more than one application, provided that each application is sufficiently distinct from any other administrative supplement application currently under consideration by the awarding NIH Institute or Center.



    Funding Type





    Medical - Basic Science
    Medical - Clinical Science
    Social Sciences

    External Deadline

    February 20, 2019