Advanced Research Projects Agency for Health (ARPA-H) Open-Office Broad Agency Announcement (BAA)

Funding Agency:
National Institutes of Health

The mission of ARPA-H is to accelerate better health outcomes for everyone by supporting the development of high-impact solutions to society's most challenging health problems. Awardees will develop groundbreaking new ways to tackle health-related challenges through highpotential, high-impact biomedical and health research. With a scope spanning the molecular to the societal, ARPA-H seeks proposals that aim to rapidly achieve better health outcomes across patient populations, communities, diseases, and health conditions, including in support of the Cancer Moonshot. Proposals are expected to use innovative approaches to enable revolutionary advances in science, technology, or systems.

ARPA-H will also foster innovations that are entirely novel proofs of concept or contribute directly to advance the goals of government-wide initiatives such as the Cancer Moonshot; Advancing the American Bioeconomy; Clinical Trial Readiness; the National Strategy on Hunger, Nutrition, and Health; the National Action Plan for Combatting Anti-Microbial Resistance; or unity agenda priorities on addressing mental health and curbing the opioid epidemic.

Abstract Due Date: March 14, 2024

Agency Website

Areas of Interest

ARPA-H has identified four initial focus areas that are a priority for investment:

(1) Health Science Futures;

(2) Scalable Solutions;

(3) Proactive Health;

(4) Resilient Systems;

as well as targeted investments in tools that enable quantitative measurements of health outcomes, promote end-user adoption, facilitate participatory research, and advance relevant Ethical, Legal, and Societal Implications (ELSI) topics. ARPA-H may also consider submissions outside of these thrust areas if the proposal involves the development of a novel capability to improve health outcomes or prolong well-being, especially if it would help either a substantial number of people or a population that currently lacks effective treatment options.

ARPA-H will foster innovations across the spectrum of technology readiness – from foundational science to the introduction of new prototypes into the marketplace. To receive funding, efforts must align with ARPA-H’s mission to accelerate better health outcomes and undertake research that cannot otherwise be pursued within the health funding ecosystem due to the nature of the technical risk.

Eligibility Requirements

All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by ARPA-H.

Entities with more than three ongoing concurrent awards with ARPA-H will not be eligible for award. The Director of ARPA-H may waive the award preference, but only if the requirements cannot reasonably be met and the proposing entity has the potential to advance ARPA-H’s statutorily defined goals.

Funding Type





Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

March 14, 2024