Advancing Technologies to Improve Delivery of Pharmacological, Gene Editing, and other Cargoes for HIV and SUD Mechanistic or Therapeutic Research (R01 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The purpose of this notice of funding opportunity (NOFO) is to develop technologies to improve the delivery of pharmacological, gene editing, or other cargoes for HIV and substance use disorder (SUD) mechanistic or therapeutic research.

This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material.


  • Letter of Intent Due Date: October 15, 2024
  • AIDS Application Due Date:  Nov. 15, 2024

RFA-DA-25-022 Expiration Date November 16, 2024

Agency Website

Amount Description

NIDA expects to fund 4 to 6 projects in FY2022 totaling $2,000,000 in direct cost. NIDA expects to fund 4 to 6 projects in FY 2023 totaling $2,000,000 in direct cost.

Funding Type





Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

November 15, 2024