This Funding Opportunity Announcement (FOA) solicits grant applications that propose research that can be translated into interventions in order to reduce infection and transmission of HIV in patients with alcohol use disorders.
Deadlines:
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Letter of Intent Due Date(s): October 17, 2020
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AIDS Application Due Date(s): November 17, 2020
RFA-AA-20-009 Expiration Date November 18, 2020
Areas of Interest
The FOA will solicit applications that address HIV and alcohol-related morbidity and mortality, and interventions that reduce the impact of alcohol on HIV disease progression and transmission.
Examples include studies that seek to:
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- Develop interventions that combine behavioral and biological strategies leading to significant and sustainable reductions in the impact of alcohol on viral load and the spread of HIV, and other effective strategies that focus on addressing long-term underlying pathophysiology.
- Discover innovative approaches to measure and treat HIV and alcohol misuse in diverse populations who continue high-risk patterns of harmful or hazardous drinking across the lifespan and may have Alcohol Use Disorders.
- Develop strategies to prevent HIV- and common alcohol-associated coinfections (e.g. COVID-19, hepatitis C, tuberculosis) and reduce comorbidities, co-infections, and complications (CCC) that are also common (e.g. tobacco and depression) among PLWH.
- Support and advance novel research to address and mitigate underlying alcohol and HIV-associated medical and social inequalities that diminish the health and well-being of PLWH in underserved and marginalized communities in domestic and international settings.
- Pursue innovative research methods and the use of new and improved technologies to facilitate advances across the research agenda and to improve the translation of basic behavioral and biological research findings into clinical and community practice.
- Use of emerging new methodologies focused on analysis and representation of large/complex datasets could also be explored, particularly in relationship to the use of electronic medical records and/or other sources of reliable information related to engagement in care.
- Advance the understanding of how the severity of alcohol use (including Alcohol Use Disorders) impacts clinical outcomes for PLWH and identify new ways of engaging and retaining this target population in effective treatment.
- Examine the additive or synergistic impact for specific comorbidities in determining clinical outcomes for PLWH who have sustained organ and tissue damage due to past alcohol use (sick quitters) and understand the optimal recovery process.
Amount Description
The application budget must not exceed $1,000,000 in direct costs per year.
The maximum project period is 5 years.