Alcoholic Hepatitis Clinical and Translational Network – Clinical Pilot Trials (U01)

Funding Agency:
National Institutes of Health

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) seeks to continue support of the previously funded program on “Translational Research in Alcoholic Hepatitis” to accelerate the discovery and validation of new diagnostic and treatment options for patients with Alcoholic Hepatitis (AH). This initiative, via a set of five FOAs, aims to enhance and consolidate the existing program into “AH Clinical and Translational Network”, hereafter termed “AH Network”. This consolidated program will consist of 1) Clinical component, 2) Data Coordinating Center, 3) Translational component, and 4) Basic and pre-clinical component.

Through this FOA, applications are sought to conduct investigator-initiated single-center feasibility and pilot studies aimed to optimize critical elements for full-scale clinical trial in patients with AH under the U01 Research Project – Cooperative Agreements funding mechanism.

Only one application per institution is allowed.

Companion FOAs:

RFA-AA-18-002U01 Research Project – Cooperative Agreements (Institutionally Limited)
RFA-AA-18-003U01 Research Project – Cooperative Agreements
RFA-AA-18-004U24 Resource-Related Research Projects – Cooperative Agreements (Institutionally Limited)
RFA-AA-18-006UH2/UH3 Phase Innovation Awards Cooperative Agreement


  • Duke Internal Deadline: September 6, 2017
  • Letter of Intent (not required) Due Date(s): September 23, 2017
  • Application Due Date(s): October 23, 2017

RFA-AA-18-005 Expiration Date October 24, 2017

Agency Website

Amount Description


Funding Type





Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

Internal Nomination

Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF.

* A letter of support from dean or chair - 1 to 1.5 pages
* Project summary - 2 to 4 pages
* CV or Biosketch of project leader

Please submit internal materials through My Research Proposal. (Code ILN)

Instructions for setting up your account and uploading internal applications can be found here: Instructions_FINAL.pdf

Internal Deadline

September 6, 2017

External Deadline

October 23, 2017