Alzheimer's Disease Translational Center for Disease Model Resources (U54)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites U54 Cooperative Agreement applications aiming to establish an Alzheimer’s Disease Translational Center for Disease Model Resources. The purpose of the Center is to: develop the next generation of rodent animal models of AD; conduct extensive characterization and clinico-pathological staging of AD animal models using translatable biomarkers; develop translatable pharmacodynamic  biomarkers for well validated therapeutic targets; develop and implement guidelines for standardized best practices  for the rigorous preclinical testing  of AD candidates; conduct preclinical testing  of candidate AD therapeutics and transparent reporting.


  • Letter of Intent Due Date(s): December 11, 2015
  • Application Due Date(s): January 11, 2016, by 5:00 PM local time of applicant organization.

​RFA-AG-16-014 Expiration Date January 12, 2015

Agency Website



Amount Description

An application may request a budget of up to $3.5 million direct costs per year.  Budgets should reflect the actual needs of the proposed project.

An application may request a project period up to five years.  

Funding Type





Medical - Translational

External Deadline

January 11, 2016