Sponsor Deadline
Posted: 4/18/2022

Asthma and Allergic Diseases Cooperative Research Centers (U19 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications from single institutions or consortia of institutions to participate in the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program. The program will support centers that integrate clinical and translational research to conduct studies on the mechanisms underlying the onset and progression of diseases of interest, including asthma, rhinitis (allergic and non-allergic), chronic rhinosinusitis, atopic dermatitis, food allergy, and drug allergy. The overarching goal of the program is to improve the understanding of the pathogenesis of these conditions and to provide a rational foundation for new, effective treatments and prevention strategies.

Only one application per institution is allowed. 


  • Duke Internal Deadline:  Interested applicants from within Duke should contact dukeiln@duke.edu as early as possible.
  • Letter of Intent Due Date: 30 days prior to the application due date​
  • Application Due Date(s): June 3, 2022

RFA-AI-21-079 Expiration Date June 4, 2022   

Eligibility Requirements

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide.

Note that the multiple PD(s)/PI(s) option may be used only for the Overall Program. Projects are limited to a single project lead per project and a single core lead per core within the multi-component application.

An investigator can serve as a PD/PI on only one AADCRC award or application. This includes all PD(s)/PI(s) of a multiple-PD/PI application.

Note that the current FOA will not allow foreign clinical trial sites. However, foreign components that will be allowed include mechanistic projects, observational studies, specialized assay, etc.

Amount Description

Application budgets are limited to $900,000 in direct costs per year and need to reflect the actual needs of the proposed project.

The scope of the proposed project should determine the project period. The maximum project period is 5 years. 


Internal Nomination

Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF.

  • NIH Biosketch of project leader
  • Draft of the following:
    • Project Summary/Abstract – 30 lines of text
    • Project Narrative – three sentences
    • Specific Aims – 1 page

Applicants will need to submit internal materials through My Research Proposal.(Code ILN) http://www.grantinterface.com/sl/u1S7Ic

Instructions for setting up your account and uploading internal applications can be found here: https://ors.duke.edu/sites/default/files/Applicant Instructions_FINAL.pdf