Biosystems Design to Enable Next-Generation Biofuels and Bioproducts

Funding Agency:
Department of Energy

Biological and Environmental Research (BER) of the Office of Science (SC), U.S. Department of Energy (DOE) hereby announces its interest in receiving applications for research of interest to the Genomic Science Program ( in the following research areas:

a) Integrating large-scale systems biology data to model, design, and engineer microbial systems for the production of biofuels and bioproducts: Interdisciplinary approaches to develop innovative, high-throughput modeling, genome-wide design and editing, and engineering technologies for a broad range of microbes relevant for the production of biofuels and bioproducts from biomass.

b) Plant systems design for bioenergy: To develop novel technologies for genome-scale engineering to re-design bioenergy crops that can grow in marginal environments while producing high yield of biomass that can be easily converted to biofuels and bioproducts.

Applications should include strategies to address biocontainment, minimizing risks of potential release of engineered organisms into the environment or other unintended outcomes. 


  • Required Pre-application: Dec. 19, 2016
  • Application: Mar. 20, 2017

Agency Website



Amount Description

It is anticipated that up to $15 million will be available for multiple awards to be made in Fiscal Year 2017, with an additional $15 million available per year, up to five years, contingent on the availability of appropriated funds. The number of awards will be contingent on satisfactory peer review, the availability of appropriated funds, and the size of the awards. Multiple year funding is expected. Applications may request project support for up to five years, with out-year support contingent on the availability of funds, progress of the research, and programmatic needs. Annual budgets are expected to range from $1,000,000 to $5,000,000 in total costs.

Funding Type





Engineering and Physical Sciences
Environmental & Life Sciences

External Deadline

December 19, 2016