BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed)

Funding Agency:
National Institutes of Health

The common marmoset (Callithrix jacchus) has emerged as a promising nonhuman primate model system to understand the primate brain. This has come about both from the realization that the behavior of the common marmoset is similar in some ways to human behavior and from recent demonstration of germline transmission of exogenous genetic information.

This Notice of Funding Opportunity (NOFO) solicits applications to expand existing colonies of the common marmoset for neuroscience research in the United States, and to support the care, breeding and distribution of genetically modified marmosets, and cryopreserved embryos and gametes created by NIH-funded research programs such as the NIH BRAIN Initiative Tools for Germline Gene Editing in Marmosets research consortium.

Recipients under this NOFO are expected to expand their current marmoset colonies to provide healthy, well-characterized animals that will be made available to the neuroscience research community, and to include a plan to accept genetically modified marmosets, and cryopreserved embryos and gametes for distribution to the research community. Recipients  are also expected to participate in and provide health and genetic information to an NIH-Funded Marmoset Coordination Center to help the community understand the pedigree of individuals in the captive marmoset population and improve the genetic diversity of that population across multiple colonies.

This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation.  Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. 

Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material. 


  • Letter of Intent Due Date(s): February 01, 2024

  • Application Due Date: March 01, 2024

RFA-MH-25-115 Expiration Date March 02, 2024




Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

March 1, 2024