BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Basic Experimental Studies with Humans Required)

Funding Agency:
National Institutes of Health

This FOA will support integrated, interdisciplinary research teams that focus on examining dynamic circuit functions related to behavior, using advanced and innovative technologies. The FOA will support programs with a necessarily-synergistic, team science approach. Awards will be made for 5 years, with a possibility of one competing renewal. Applications should focus on overarching principles of circuit function in the context of specific neural systems underlying sensation, perception, emotion, motivation, cognition, decision-making, motor control, communication, or homeostasis. Applications should aim to understand these circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating relevant dynamic patterns of neural activity and by measuring the resulting behaviors and/or perceptions. Applications are expected to employ approaches and experimental design guided by specified theoretical constructs, are encouraged to employ quantitative, mechanistic and predictive models where appropriate. Model systems, including the possibility of multiple species ranging from invertebrates to humans, can be employed and should be appropriately justified. Programs should employ multi-component teams of research expertise – including neurobiologists, statisticians, physicists, mathematicians, engineers, computer scientists, and data scientists, as appropriate - that seek to cross boundaries of interdisciplinary collaboration. Applications will be required to manage their data and analysis methods in a framework that will be developed and used in the proposed U19 project and exchanged with other BRAIN U19 awardees for further refinement and development.

Companion FOA: RFA-NS-22-040, BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Not Allowed)


  • Letter of Intent Due Date(s): 30 days prior to application due date
  • Application Due Date(s): Sep. 16, 2022; Sep. 15, 2023; Sep. 13, 2024

​RFA-NS-22-039 Expiration Date September 14, 2024

Agency Website

Eligibility Requirements

Applications submitted in response to this solicitation may not duplicate or be substantially similar to other applications concurrently under consideration by other programs or study sections including the inter-agency programs such as Collaborative Research in Computational Neuroscience (CRCNS), EArly-concept Grants for Exploratory Research (EAGER) or Next Generation Networks For Neuroscience (NeuroNex). Duplicate or substantially similar applications will be withdrawn.    

Funding Type





Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science

External Deadline

September 15, 2023