CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites applications for basic research projects on chemical warfare agents, toxic industrial chemicals, and pesticides that have primary or secondary effects on the nervous system. Chemical threats are toxic compounds that could be used in a terrorist attack or accidentally released from industrial production, storage, or shipping. Projects supported by this FOA are expected to generate data that elucidate mechanisms of toxicity of these agents, possible new manifestations of toxic exposures, and potential new targets for therapeutic development.


  • Letter of Intent: 30 days before the application due date
  • Application: Oct 27, 2022; May 30, 2023; Oct 17, 2023

PAR-23-027 Expiration Date October 18, 2023

Agency Website

Amount Description

Application budgets may not exceed $300,000 in direct costs per year.

Many applications will not need to request the maximum budget and the requested budget will need to reflect the actual needs of the proposed project.

The maximum project period is 3 years.

Funding Type





Engineering and Physical Sciences
Medical - Basic Science

External Deadline

October 17, 2023