Center for Alternatives to Animal Testing -- CAAT Science-Based Refinement Awards

Funding Agency:
Johns Hopkins University

Attention veterinarians, lab technicians, animal technicians, and all who work with laboratory animals: The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) now is accepting proposals for the 2017 Science-based Refinement Awards (formerly the Animal Welfare Enhancement Awards).

The focus of these awards is to elicit scientific evidence to support the enhancement of the housing, handling and/or experimental situations for laboratory animals. Studies may, for example, examine:

  • how physiological and behavioral stress responses to common husbandry (e.g., capture) and traditional treatment procedures (e.g., gavage, injection, blood collection) can be reduced or eliminated (e.g., by training the subjects to cooperate rather than resist);
  • whether animals caged at different tier levels show different physiological and behavioral stress responses when being approached by personnel, and how these responses can be minimized or avoided;
  • whether the presence of a compatible companion buffers physiological and behavioral stress responses to experimental situations (e.g., enforced restraint);
  • whether animals kept in legally minimum-sized cages benefit from a moderate increase in space that is (a) empty versus (b) structured in species-appropriate ways (e.g., shelter, visual blind, perch, platform, PVC tube).

Any studies to be undertaken must be non-invasive, with the possible exception of obtaining blood for biochemical measurements (animals that have been trained to cooperate during venipuncture should be used, if possible). Objective measures might include behavior, coat appearance, body weight, analysis of feces, urine, or blood as described above. Preference will be given to studies that have broad applicability.

Each award will be for $6,000. There are no F&As allowed on this award.

These awards are intended for veterinarians and laboratory and animal technicians.

Deadline: Dec. 31, 2018

Agency Website



Funding Type





Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science

External Deadline

December 31, 2018