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Center for the Investigation of Factor VIII (FVIII) Immune Response in Patients with Hemophilia A (U54)
The goal of this Funding Opportunity Announcement (FOA) is to establish up to four Centers for the Investigation of Factor VIII immunogenicity (FVIII Centers). These Centers will utilize cross-disciplinary science and novel technologies to define the basic mechanisms involved in the development of anti-FVIII neutralizing antibodies, also known as FVIII inhibitors, in patients with congenital hemophilia A.
Applications will also include a Skills Development component to support the development of interdisciplinary research skills and expertise in the next generation of physicians/scientists in the field of hemostasis, including the entire spectrum of blood sciences. One application will be selected from the awarded FVIII Centers to provide a range of administrative support to all awardees through an Administrative Core.
- Letter of Intent Due Date(s): June 6, 2017
- Application Due Date(s): July 6, 2017
RFA-HL-18-014 Expiration Date July 7, 2017
Application budgets may not exceed direct costs of $930,000 per year in fiscal years 2018 through 2022.
The maximum period of support is 5 years.