Sponsor Deadline
Posted: 3/19/2024

Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)

The Centers of Excellence in Genomic Science (CEGS) program establishes academic Centers for advanced genome research. Each CEGS award supports a multi-investigator, interdisciplinary team to develop integrated, transformative genomic approaches to address a biomedical problem. A CEGS project will address a critical issue in genomic science, genomic medicine, or computational genomics, proposing a highly innovative solution that would be a major advance. The research will entail substantial risk, balanced by outstanding scientific and management plans and very high potential payoff. A CEGS will focus on the development of novel technological or computational methods for the production or analysis of comprehensive data sets, on a genome-scale biomedical problem, or on other ways to develop and use genomic approaches for understanding biological systems or furthering the application of genomic knowledge, data, and methods towards clinical applications. Each CEGS will nurture genomics by facilitating the interaction of investigators from several disciplines. Along with its scientific goals, CEGS will also expand the pool of genomic scientists and engineers that can use and apply the novel methods, concepts, and knowledge developed by the CEGS by providing education and outreach experiences to scientists at all career levels.


  • Letters of Intent Receipt Date(s):  While letters of intent are normally requested 30 days before the application due date, for this FOA they are requested on May 11, 2023; May 10, 2024.
  • Application Receipt Dates(s): June 23, 2023; June 21 2024; June 23, 2025

PAR-23-098 Expiration Date: New Date June 24, 2025 (Original Date: June 22, 2024) per issuance of NOT-HG-24-015

Amount Description

Applicants may request up to $1.5 million direct costs for any year for continuing operations (e.g., personnel, standard laboratory equipment, supplies, travel, consortia, and other expenses). Inflationary adjustments will not be allowed. Budgets must reflect the actual needs of the proposed project.

A CEGS application may request up to five years of support. The maximum length of support for a Center under this program (with a renewal) is ten years.