Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

The NICHD has a state-of-the-art Chemical Synthesis and Optimization Facility for advancing male and/or female non-hormonal contraception development with the capabilities and capacity for preclinical services including Investigational Device Exemption (IDE) or Investigational New Drug (IND)-enabling studies (e.g., protein generation, high throughput screening, structure activity relationships, hit-to-lead generation, drug metabolism, fertility studies).

The purpose of this FOA is to provide investigators with a mechanism to request services from this facility that would advance their development program for either male or female contraceptives.


  • Letter of Intent Due Date(s): 30 days before application due date.
  • Application Due Date(s): July 1, 2019, December 16, 2019, May 1, 2020, December 15, 2020, May 3, 2021, and December 13, 2021

PAR-19-261 Expiration Date December 14, 2021




Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

May 1, 2020