Childhood Asthma in Urban Settings -Clinical Research Centers (U01 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the NIAID Childhood Asthma in Urban Settings Clinical Research Network Clinical Research Centers (CAUSE-CRCs). The CAUSE-CRCs will conduct both network-wide and site-specific clinical studies and trials with the ultimate goal of developing effective asthma treatment or prevention approaches applicable to children residing in low-income urban settings. For network-wide clinical research projects and other network functions, the CAUSE-CRCs will work closely with the CAUSE Leadership Center (CAUSE-LC).


Only one application per institution (normally identified by having a unique DUNS number or NIH IPF number) is allowed.


  • Duke Internal: March 20, 2020
  • Letter of Intent: 30 days prior to the application due date
  • Application: June 19, 2020

RFA-AI-19-073 Expiration Date: June 20, 2020

Agency Website

Eligibility Requirements

Applicants may submit to both the CAUSE-CRC (RFA-AI-19-073) and the CAUSE-LC (RFA-AI-19-074) funding opportunities. However, different clinical projects must be proposed in each of the two applications.



Amount Description

Application budgets are limited to $300,000 in direct costs and need to reflect the actual needs of the proposed projects.

The proposed project period must be 7 years.

    Funding Type





    Environmental & Life Sciences
    Medical - Clinical Science
    Medical - Translational

    Internal Nomination

    Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF.

    • NIH Biosketch of PI
    • Specific Aims (1 page)
    • List names of individuals/organizations from which letters of support/commitment will be requested (see Letters of Support under Section IV of the solicitation for details)

    Please submit internal materials through My Research Proposal. (Code ILN)

    Instructions for both creating an account (if you don't already have one) and submitting your materials can be found here:

    Internal Deadline

    March 20, 2020

    External Deadline

    June 19, 2020