This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Clinical trials utilizing telehealth or other decentralized / remote strategies are encouraged to apply.
Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals, diagnostics or cellular/gene therapies, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in the clinic as standard of care.
LOI SUBMISSION DEADLINE: MAY 8, 2024