Collaborative Centers in Children's Environmental Health Research and Translation (P2C Clinical Trial Optional)

Funding Agency:
National Institutes of Health

To accelerate the movement of research findings to action, NIEHS invites grant applications from institutions/organizations that propose to build a Collaborative Center in Children's Environmental Health Research and Translation (CEHRT Center). Centers are charged with developing effective strategies to translate key children's environmental health (CEH) research findings to relevant stakeholders in the community, academia and practice.

The overall goal of this FOA is the creation of a national network of children's environmental health translation centers. Through external collaboration with the children's environmental health community, Centers will protect and improve children’s health by developing and testing new scientific questions and public health interventions/strategies with an eye towards translation; and mentoring a pipeline of new investigators interested in translational CEH.

CEHRT centers will serve as leaders in CEH translational research and research methodology development, with a focus on creating actionable steps to move evidence-informed biomedical, behavioral, psychosocial, environmental research findings in children's environmental health to the wider community. The collective collaborative center program will also serve as a national research resource to support response efforts to emerging environmental exposures affecting children.

Only one application per institution is allowed.


  • Duke Internal: July 23, 2020
  • Letter of Intent Due Date: October 23, 2020
  • Application Due Date(s): November 23, 2020

RFA-ES-20-001 Expiration Date November 24, 2020

Agency Website

Areas of Interest


Eligibility Requirements

There are additional eligibility criteria for applications responding to this FOA:

Multi-PD/PI required: One recognized and established research investigator in CEH (Director), and an expert (referred to as Deputy Director) with a track record in health communication with translation of science to lay audience, scientific community and public health and or medical professionals.

Active Scientists.  Applicants must have active scientists working in children's environmental health that is within the scientific mission of NIEHS.  Active CEH scientists must hold their primary affiliation with applicant institution or other institutions and this position (tenured or nontenured) must be permanent; Applicants need to have a strong record in scientific publications and competitiveness for peer-reviewed external funding for research within the science mission of NIEHS in CEH. Active scientists must meet the following criteria:

(1) PD/PIs must have externally-funded active CEH grants or contracts within the three most recently completed fiscal years: 2017, 2018, 2019.  Grant awarded in FY 2020 may be included.  Federal fiscal year runs from October 1 to September 30.

(2) PD/PIs must have strong CEH research publications in peer-reviewed journals during the three most recently completed Federal fiscal years, including FY2019.

Funding by the NIEHS. 

(1) Each application must have and identify at least three active PD/PIs  who have received a research grant or other significant funding from NIEHS within the three most recently completed Federal fiscal years in the area of children's environmental health at the time of submission (FY 2017, 2018, and 2019.  The mechanisms that qualify are research projects (R01, R21, R00, R15), research program projects (P01, P50, P42), and individual research career development awards for faculty (K24, K08, K23).

(2) Mechanisms that do not qualify are individual pre-doctoral and/or post-doctoral fellowships (e.g., F31, F32, K99), T awards, U45, Conference grants (e.g., R13, U13) and R24, U24, P30 or U2C grants funded by NIEHS.  Furthermore, grants and cooperative agreements in extension periods, either with or without additional funds, as well as supplements of any kind, do not count toward this requirement.   

      Amount Description

      Applicants may request direct costs up to $500,000 per year. Because the nature and scope of the proposed infrastructure will vary, it is anticipated that the size of the awards will vary to reflect the actual needs of the proposed center.

      In addition to proposing an infrastructure center, the applicant may propose to take on the additional role of serving as the coordinating center across all the funded infrastructure centers and may request up to $100,000 in additional direct costs for this optional role. Only one coordinating center will be chosen from among the funded P2C networks.


      The total project period for an application submitted in response to this FOA may not exceed 5 years of support.


      For renewal applications, requested annual direct costs may not exceed $500,000 or the amount of annual support (direct costs) the center receives from outside the applicant institution for population dynamics research and training, whichever is lower. In addition, the requested annual increase may not exceed $125,000 of the prior competitive award.

        Funding Type





        Environmental & Life Sciences
        Medical - Clinical Science
        Medical - Translational

        Internal Nomination

        Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF.

          • LOI containing:

            • Descriptive title of proposed activity
            • Name/address/telephone number of PD(s)/PI(s)
            • Names of key personnel
            • Participating institution(s)
            • Number/title of funding opportunity
          • Specific Aims (1 page)
            • Briefly state proposed research domain(s), expertise, key resources, and specific strategies for promoting opportunities in CEH to larger scientific community/relevant stakeholders, including
            • The center's primary research area(s) in CEH supported through this program
            • A translation plan describing how Center will increase scientific impacts, innovation, productivity and translation of CEH research
            • Evidence that support will contribute to center achieving its specific aims


        Please submit internal materials through My Research Proposal. (Code ILN)


        Instructions for creating an account (if needed) and submitting your materials:

        External Deadline

        July 23, 2020