Communication and Decision Making for Individuals with Inherited Cancer Syndromes (U01 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

 Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites the submission of applications requesting support for projects that will be conducted to develop, test, and evaluate interventions and implementation approaches, or adapt existing approaches, to improve cancer risk communication between patients with an inherited susceptibility to cancer (and their families) and providers so that affected individuals can make informed clinical risk management decisions. Specifically, this FOA targets the following area designated as a scientific priority by the Blue Ribbon Panel ( Recommendation G ( ): "Sponsor initiatives to improve the current state of early detection, genetic testing, genetic counseling, and knowledge landscape of the mechanisms and biomarkers associated with cancer development and conduct implementation science research to accelerate development, testing, and broader adoption of proven strategies to significantly reduce cancer risk and address cancer health disparities in these areas."

Projects that: (1) focus on delivery of culturally competent genetic counseling, especially with respect to members of underserved populations; or (2) test approaches to communicate uncertain genetic test results to individuals with an inherited susceptibility to cancer (and their families) and examine those individuals' behavioral, psychological, and clinical outcomes are considered high priority.


  • Letter of Intent Due Date(s): 30 days prior to the application due date
  • Application Due Date(s): January 21, 2020

RFA-CA-20-006 Expiration Date  January 22, 2020  

Agency Website



Amount Description

Application budgets are limited to $600,000 in direct costs per year and need to reflect the actual needs of the proposed project.

The scope of the proposed project should determine the project period. The maximum project period is 5 years. 

    Funding Type





    Medical - Clinical Science
    Social Sciences

    External Deadline

    January 21, 2020