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Congressionally Directed Medical Research Programs (CDMRP) -- Duchenne Muscular Dystrophy Research Program -- Investigator-Initiated Research Award
The DMDRP Investigator-Initiated Research Award (IIRA) supports translational research that will accelerate the movement of promising ideas in Duchenne research into clinical applications. Translational research may be defined as an integration of basic science and clinical observations with the specific goal of developing new therapies. The ultimate goal of translational research is to move a concept or observation forward into clinical application. However, Principal Investigators (PIs) should not view translational research as a one-way continuum from bench to bedside. The research plan should involve a reciprocal flow of ideas and information between basic and clinical science. Within this continuum, the IIRA supports later-stage translational research projects, including early-phase, proof-of-principle clinical trials and correlative studies to better inform development of drugs, devices, and other interventions. Research projects may also include preclinical studies utilizing animal models, human subjects, or human anatomical substances
• Pre-Application Deadline: August 29, 2018
• Invitation to Submit an Application: October 2018
• Application Submission Deadline: December 5, 2018
Areas of Interest
• The PI must be at or above the level of Assistant Professor (or equivalent).
• The OIC must be at or above the level of Assistant Professor (or equivalent). The OIC is required to devote a minimum of 10% level of effort to this project.
• The PI and OIC must be independent investigators whose primary training, research, and experience are in different fields.
• Optional Nested Resident or Medical Student Traineeship: By the time of the application submission deadline, the Resident Trainee must be enrolled in an accredited residency program, or the Medical Student Trainee must be enrolled in a nationally accredited (or equivalent) medical school. The trainee must be able to devote a minimum of 40% level of effort to this project for the 1-year period of performance of the traineeship.
The anticipated direct costs budgeted for the entire period of performance for an FY18 DMDRP IIRA will not exceed $600,000 or $750,000 if applying for the IIRA with an OIC. Additional funding can be requested above the maximums specified for the IIRA or the IIRA with an OIC to specifically support the Optional Nested Resident or Medical Student Trainee. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.