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Posted: 3/26/2024

Congressionally Directed Medical Research Programs (CDMRP) -- Epilepsy Research Program -- Virtual Post-Traumatic Epilepsy Research Center Faculty Award

The ERP seeks to solicit Faculty members to join the Virtual Post-Traumatic Epilepsy Research Center (P-TERC) in order to advance PTE research through development of early-career investigators and investigators new to the PTE field. The ERP Virtual P-TERC is a unique, interactive virtual research center providing intensive mentoring, national networking, collaborations, and a peer group for new PTE investigators. The overarching goal of the Virtual P-TERC is to develop successful, highly productive PTE researchers in a collaborative research and career development environment to enhance quality and expand quantity of the PTE research field.

Deadlines:

  • REQUIRED Pre-application Submission Deadline:  June 5, 2024
  • Full Application Submission Deadline:  June 20, 2024
Areas of Interest

To meet the intent of the funding opportunity, applications to the FY24 ERP Virtual Post-Traumatic Epilepsy Research Center Faculty (Virtual-P-TERC-F) Award should address at least one of the Focus Areas listed below. Applications may address more than one Focus Area. An application that proposes research outside of these FY24 ERP Focus Areas is also acceptable, as long as the applicant provides a strong justification as to why the topic is critical to advance understanding of PTE and how it addresses the ERP mission.

• Markers and Mechanisms: Identifying biomarkers or mechanisms of PTE, which may include the following:
○ Predictive biomarkers of epileptogenesis (acute and chronic)
○ Research into the prevention of epilepsy and/or seizures

• Epidemiology: Epidemiological characterization of PTE following TBI, which may include the following:
○ Understanding and improving the quality of life of individuals with PTE, their families, and/or their care partners
○ Predictors of the development of epilepsy
○ Outcomes, including latency to and prevention of epilepsy, comorbidities, and mortality

• Longitudinal Studies: Studies of the evolution of PTE, which may include the following:
○ Understanding and improving the quality of life of individuals with PTE, their families, and/or their care partners
○ Treatment and health care outcomes research, including quality of care
○ Comorbidities (e.g., psychiatric disorders, cognitive/physical deficits, sleep disorders, fatigue)

• Innovative Research: Tools intended to better inform or improve upon PTE research and care, which may include the following:
○ Strategies that will improve seizure detection, characterization, visualization, or diagnosis (e.g., artificial intelligence, bioinformatics, clinical databases, devices, tissue banks)
○ Development of new models or better characterization of existing etiologically relevant models for PTE

Eligibility Requirements

• Principal Investigator
○ Early-career investigators and investigators new to the PTE field may be named by the organization as PI.
○ The PI should be new to the field of PTE research as evidenced by only nominal publication and/or funding history in the field.

• Career Guide
○ Must hold a position at or above the level of an associate professor (or equivalent).
○ Must be a researcher that possesses qualifications, background, and experience relevant to the proposed research project as well as a track record for mentoring investigators in the field.
○ There is no limit on the number of applications for which an individual may be named as Career Guide.
○ The Director and Deputy Director of the Virtual P-TERC cannot be listed as a Career Guide.

The PI and Career Guide DO NOT need to be located at the same organization.

Amount Description

The anticipated direct costs budgeted for the entire period of performance for an FY24 Virtual P-TERC-F Award should not exceed $525,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.