Congressionally Directed Medical Research Programs (CDMRP) -- Neurofibromatosis Research Program -- New Investigator Award

Funding Agency:
Department of Defense

The intent of the NFRP New Investigator Award is to support the continued development of promising early-stage investigators and/or the transition of established investigators from other research fields into a career in the field of NF research. Prior experience in NF research is not required. However, Principal Investigators (PIs) with a limited background in NF research are strongly encouraged to have a collaborator who is experienced in the NF field.

• Required Pre-Application Submission Deadline:  June 25, 2020
• Application Submission Deadline: July 9, 2020

Agency Website

Areas of Interest

The vision of the FY20 NFRP is to decrease the clinical impact of NF. Toward this end, the NFRP seeks to support innovative, high-impact research that will foster new directions for and address neglected issues in NF research; sponsor multidisciplinary and multi-institutional collaborations that will bring new perspectives to the field; promote translational and clinical studies to move promising ideas from bench to bedside; and develop a balanced portfolio of meritorious research related to all aspects of NF1, NF2, and schwannomatosis.

Areas of Emphasis:

  • Biomarker discovery, utility, development, and validation
  • Non-tumor manifestations including but not limited to: ○ Pain ○ Cognitive manifestations ○ Sleep
  • Heterogeneity of NF-related tumors 
  • Novel disease and treatment response markers using genetics, genomics, epigenetics, systems biology, metabolomics, or similar approaches
  • Preclinical efficacy studies
  • Target identification, drug discovery
  • Nutritional, environmental, and other modifiers of NF
  • Health services research

Eligibility Requirements

• Graduate students, postdoctoral fellows, and other “mentored” researchers are not eligible for this award.

• PIs must be either:

○ Early-Stage Investigator

  • An independent investigator at or below the level of Assistant Professor (or equivalent);
  • Must commit at least 30% of his/her effort toward the proposed NF research project. 

○ Established Investigator

  • An established independent investigator in an area other than NF at or above the level of Assistant Professor seeking to transition to a career in NF, thereby bringing his/her expertise to the field.
  • Must commit at least 10% of his/her effort toward the proposed NF research project.

• PIs must not have received more than $300,000 in total direct costs for previous or concurrent NF research as a PI of one or more Federally funded, non-mentored peer reviewed grants;

• PIs must not have received a New Investigator Award previously from any program within the CDMRP.



Amount Description

The anticipated direct costs budgeted for the entire period of performance for an FY20 NFRP New Investigator award will not exceed $450,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

Funding Type



Junior Faculty


Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

June 25, 2020