Congressionally Directed Medical Research Programs (CDMRP) -- Peer Reviewed Orthopaedic Research Program (PRORP) -- Integrated Clinical Trial Award

Funding Agency:
Department of Defense

The PRORP Integrated Clinical Trial Award (ICTA) supports the rapid implementation of an interdisciplinary clinical trial that integrates both surgical and rehabilitation strategies and has the potential to have a major impact on the treatment of combat-related orthopaedic injuries and/or the treatment of non-battle injuries that significantly impact unit readiness and return-to-duty/- work rates.  

Projects that follow patients across the continuum of care are highly encouraged. The projects should include both surgical and rehabilitation strategies that create a cohesive project. Surgical strategies are reconstruction and repair and/or application of biologics, pharmaceuticals, and devices for the purpose of restoration of native architecture, composition, and function of traumatically injured tissues. Rehabilitative strategies are those that restore function following injury or illness, with the goal of optimal health and independence. Projects should integrate principles and approaches from surgical and rehabilitative strategies, beyond what each approach would result in alone, with the goal of optimizing form, function, and independence for those who have sustained traumatic orthopaedic injuries. Care should be taken to avoid or account for confounding factors in the analyses.


• Pre-Application Deadline:  July 12, 2017

• Invitation to Submit an Application: August 16, 2017

• Application Submission Deadline:  September 27, 2017

Agency Website

Eligibility Requirements

The PI must be an independent investigator at or above the level of Assistant Professor (or equivalent). It is expected that the expertise of the PI and Qualified Collaborator(s) will be complementary covering orthopaedic rehabilitation as well as orthopaedic or trauma care. One investigator must be a clinician with the appropriate expertise. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by, or affiliated with, an eligible organization.

Funding Type



Junior Faculty


Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

July 12, 2017