To meet the intent of the award mechanism, applications must address at least one of the FY23 CPMRP IIRA Focus Areas. Selection of the appropriate focus area is the responsibility of the applicant.
• Chronification of pain ○ Understanding mechanisms of, and developing models for studying, the transition from acute to chronic pain. ○ Development of therapies to prevent and treat chronification ○ Identifying risk or protective factors or biomarkers for treatment response or patient susceptibility to chronification. ○ Investigating relationships between pain and its comorbidities that can contribute to the development/progression of chronic pain
• Development of non-opioid therapies and methods for the treatment of chronic pain o Novel non-mu-opioid pharmacological therapies o Devices or procedures that treat chronic pain directly o Devices or procedures that improve the administration of non-opioid analgesics
Independent Investigators at all levels may be named by the organization as the PI on the application. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by or affiliated with an eligible organization.
The anticipated direct costs budgeted for the entire period of performance for an FY23 CPMRP Investigator-Initiated Research Award should not exceed $900,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.