Congressionally Directed Medical Research Programs -- Chronic Pain Management Research Program -- Clinical Outcomes Research Award

Funding Agency:
Department of Defense

The intent of the FY23 CPMRP CORA is to support studies focused on improving clinical outcomes through late-stage translational efforts that will accelerate the movement of evidencebased ideas in chronic pain management into clinical applications, such as health care products, technologies, clinical practice guidelines, and/or models of care. CORA applications should explain how the proposed work will inform the development, refinement, and/or revision of existing standards of care, recommendations, or guidelines for managing chronic pain. The FY23 CPMRP CORA is focused on identifying and implementing outcomes-based best practices through the analysis of the merits of pain management approaches, not on the development of new or novel techniques. Studies seeking to advance new and novel opioid-based therapeutic interventions do not meet the intent of the award mechanism and will not be selected for funding. Studies seeking to understand and reduce opioid utilization in chronic pain management within the context of current prescribing practices are acceptable.


  • Required Pre-Application Deadline:   August 21, 2023
  • Invitation to Submit an Application: Sep. 2023
  • Application Submission Deadline:  Nov. 9, 2023

Agency Website

Areas of Interest

To meet the intent of the award mechanism, applications must address at least one of the FY23 CPMRP CORA Focus Areas. Selection of the appropriate focus area is the responsibility of the applicant.

• Implementation science (for evidence-based, efficacious interventions to manage or prevent chronic pain) o Unique barriers for Service Members, Veterans, and beneficiaries, including at-risk subpopulations o Self-management and service-of-care models o Interventions to prevent chronification of pain

• Comparative effectiveness (for evidence-based, efficacious interventions to manage or prevent chronic pain) o Multimodal, integrative, and combination therapies o Relationships between comorbidities and pain o Preventing chronification of pain

• Observational studies related to chronic pain o Predictor studies of outcomes from long-term opioid use o Predictors of or against pain chronification o Evaluation of health care use patterns (e.g., systems, interventions, treatments) o Relationships between comorbidities and pain

Eligibility Requirements

Investigators at or above the level of Assistant Professor (or equivalent) may be named by the organization as the PI or Partnering PI on the application. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by or affiliated with an eligible organization.



Amount Description

The anticipated direct costs budgeted for the entire period of performance for an FY23 CORA should not exceed $1.4M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

Funding Type



Junior Faculty


Medical - Clinical Science
Medical - Translational

External Deadline

August 21, 2023