Congressionally Directed Medical Research Programs -- Combat Readiness – Medical Research Program -- Translational Research Award

Funding Agency:
Department of Defense

The CRRP seeks to increase pre-hospital survivability of the Warfighter by enabling individuals, of varying expertise, to address casualties of the battlespace and closer to the point of injury. The intent of the FY23 CRRP TRA is to support high-impact translational research that will accelerate innovative ideas into clinical applications, including health care products, technologies, and/or practice guidelines. Research funded under this award mechanism will be hypothesis-driven, high-impact applied research that is relevant to active-duty Service Members, Veterans, other military beneficiaries, and the American public.

Applicants may leverage existing resources in translational research to address high-impact research ideas or unmet needs to enable the delivery of life-saving care to the Warfighter during prolonged and en route care in austere and combat environments. For this award mechanism, the definition of “leveraging” is as follows: An investigator basing a research project on existing resources in order to amplify potential gains in knowledge or accelerate technical maturity. Research of interest may include knowledge products, “knowledge resulting from research with the potential to improve individual or public health,”2 and solutions that can accelerate the introduction of military-relevant health products or technologies into clinical and/or operational use. Projects should take into consideration the varied expertise levels of targeted medical providers, available resources, and the possible diverse environmental conditions in combat situations. Proposal/application submissions are encouraged to include characteristics relevant to military use in the pre-hospital, combat operational setting. Submissions that propose solutions to advance civilian trauma care are not precluded, since civilian trauma and trauma care in the military are mutually influential and may be co-occurring in certain situations.

Impact is a key component of this award mechanism. The potential impact of the research, both short term and long term, in addressing the FY23 CRRP Focus Area(s) should be clearly described. Successful high-impact research should lead to the rapid development and translation of applicable advances for improving medical readiness, mitigating fatalities, optimally treating life-threatening injuries, and promoting positive long-term outcomes for military health and medicine, as well as the general public.


• Required Pre-Proposal/Pre-Application Submission Deadline:  July 7, 2023

• Proposal/Application Submission Deadline:  July 20, 2023

Agency Website

Areas of Interest

Funding should be used for the research and development of one of the following Focus Areas:

• Solutions to enhance combat care delivery throughout the far-forward environment, such as: ○ Telemedicine solutions that enable medical capabilities at far-forward battlespace locations worldwide ○ Medical simulation technologies that support the sustainment of critical skills and medical decision-making ○ Blood products, including freeze-dried plasma and platelets ○ Ruggedized oxygen generation systems for medical use ○ Solutions for the assessment of mild traumatic brain injury, to include portable and handheld detection devices ○ Initial treatment and transport of patients with highly transmissible infectious diseases

• Wound care solutions for complex trauma and tissue regeneration that span the operational medical care continuum or roles of care (e.g., acute through chronic care), such as: ○ Multi-modal wound care solutions that provide a combination of hemostasis, wound healing, infection prevention, and/or analgesia

Solutions to enhance Warfighter readiness, such as solutions to address: ○ Sleep disorders ○ Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) ○ Service-related post-traumatic arthritis ○ Eating disorders ○ Sarcoidosis ○ Valley fever ○ Complementary health measures to accelerate return to duty ○ Regenerative medicine

Eligibility Requirements

Independent investigators at all academic levels (or equivalent) are eligible to be named by the organization as the PI in the proposal/application. There are no limitations on the number of proposals/applications for which an investigator may be named as a PI. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by, or affiliated with, an eligible organization.



Amount Description

The period of performance of the CRRP TRA will be 2 years. The anticipated total costs budgeted for an FY23 CRRP TRA should not exceed $1.1M.

Funding Type





Medical - Translational

External Deadline

July 7, 2023