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Congressionally Directed Medical Research Programs -- Combat Readiness – Medical Research Program -- Rapid Development and Translational Research Award
The CRRP seeks to enhance medical capabilities at the point of greatest need in order to save the most lives in future combat scenarios, which may be complicated by limited resources, austere conditions, and/or mass casualty events. The intent of the FY19 CRRP RDTRA is to support research that will accelerate the movement of promising ideas into clinical applications, including healthcare products, technologies, and/or practice guidelines. Applicants may leverage existing resources in translational research to address high-impact research ideas or unmet needs in delivering lifesaving care to the Warfighter during prolonged and en route care in austere and combat environments. Research of interest may include knowledge products, “knowledge resulting from research with the potential to improve individual or public health,”2 and solutions that can accelerate the introduction of military-relevant health products or technologies into clinical and/or operational use. For this award mechanism, the definition of “leveraging” is as follows: An investigator basing a research project on existing resources in order to amplify potential gains in knowledge or accelerate technical maturity. Projects should consider the varied expertise levels of the medical providers and the possible diverse environmental conditions in combat situations. Proposal/application submissions are encouraged to include characteristics relevant to military use in non-hospital settings in theater, but submissions that propose solutions to advance civilian trauma care are not precluded, since civilian trauma care frequently informs and influences trauma care in the military, and vice versa.
• Required Pre-Application Deadline: October 23, 2019
• Application Submission Deadline: November 13, 2019
Areas of Interest
The Focus Areas were defined from research priorities described in the Congressional language for the CRRP in FY19. These Focus Areas broadly describe current priorities to improve readiness for delivering frontline care in combat situations and for delivering medical damage control capability, assets, and lifesaving interventions during prolonged and en route care in austere and combat environments, including the acute and early management of combat-related trauma at the point of injury. To meet the intent of the award mechanism, proposals/applications submitted to the FY19 CRRP RDTRA must address at least one of the FY19 CRRP RDTRA Focus Areas listed below.
- Scalable solutions for wound care that can address prevention of bleeding and infection, delivery of therapeutics, and promotion of healing
- Decision-support solutions, such as algorithms, artificial intelligence, deep learning, telemedicine, etc. for triage and management of severely injured Warfighters, to include management and monitoring of: ○ Acute pain, to include non-opioid solutions ○ Hemorrhage and resuscitation (e.g., airway management, control of bleeding, sedation, etc.) ○ Multi-casualty events when delayed evacuation exceeds available capability and/or capacity, in order to extend or enhance provider capabilities
- Solutions that address hemorrhage control, including: ○ Non-compressible torso hemorrhage ○ Alternatives to optimize logistics and administration of blood products to the Warfighter
- Wearable sensors with multiple capabilities to identify and monitor medical management of injuries and/or exposures, such as: ○ Environmental exposures ○ Onset of infection, including sepsis ○ Physiological status and stress monitoring tools (heart rate, blood pressure, respiration) ○ Neurological injury ○ Point-of-care imaging in prolonged field care
Independent investigators at all academic levels (or equivalent) are eligible to be named by the organization as the PI in the proposal/application. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by, or affiliated with, an eligible organization.
The anticipated direct costs budgeted for the entire period of performance for an FY19 CRRP RDTRA will not exceed $1,500,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.