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Congressionally Directed Medical Research Programs -- Hearing Restoration Research Program -- Translational Research Award
The FY18 HRRP TRA mechanism is intended to support translational research that will accelerate the movement of promising laboratory research relevant to hearing restoration into clinical applications.
The ultimate goal of translational research is to move an observation forward into clinical application and accelerate the clinical introduction of healthcare products, technologies, or practice guidelines. Observations that drive a research idea may be derived from a laboratory discovery, population-based studies, or a clinician’s first-hand knowledge of patients and anecdotal data. Principal Investigators (PIs) should not view translational research as a one-way continuum from bench to bedside. Research plans that involve a reciprocal flow of ideas and information between basic and clinical science are highly encouraged. Developmental pathways for translational research that may be useful for designing translational research studies for support under this award mechanism may be found at http://clincancerres.aacrjournals.org/ content/14/18/5664 (a report of the National Cancer Institute Translational Research Working Group).
• Pre-Application Deadline: July 17, 2018
• Application Submission Deadline: November 8, 2018
Areas of Interest
To meet the intent of the award mechanism, all applications to the FY18 HRRP TRA mechanism must address research in at least one of the following Focus Areas:
• Develop reliable in vitro human models for evaluating hearing restoration therapies.
• Accelerate translation of biological regeneration mechanisms into therapies that restore auditory function. Examples include, but are not limited to: ○ Treatments to enhance synaptic plasticity; ○ Hair cell regeneration; ○ Neural regeneration.
Tinnitus or vestibular-related research is excluded.
Independent investigators at all academic levels (or equivalent) are eligible to submit applications.
The anticipated direct costs budgeted for the entire period of performance for an FY18 HRRP TRA will not exceed $1M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.