The LRP Impact Award encourages applications that support the full spectrum of research projects or ideas that specifically focus on scientific and clinical lupus issues, which, if successfully addressed, have the potential to make a major impact in lupus research and/or lupus disease. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale that is established through inferential reasoning and/or critical review and analysis of the literature. Inclusion of preliminary data is encouraged.
Deadlines:
• Required Pre-Application Submission Deadline: July 20, 2023
• Application Submission Deadline: August 10, 2023
To be considered for funding, applications for the FY22 LRP Impact Award are required to address at least one of the following FY22 LRP Focus Areas:
• Understanding how lupus disease heterogeneity impacts risk of disease, disease presentation, clinical course, and outcomes; using a diverse range of research disciplines including, but not limited to, biopsychosocial studies, personalized medicine, variation in treatment studies, health economics, socioeconomic studies, environmental studies, systems biology, maternal fetal health and epidemiological studies
• Understanding the biological mechanisms of lupus disease including, but not limited to, studies of informative/rare patients
• Determining the pathobiology of end organ injury related to lupus disease in target human tissues
• Improving quality of life for individuals living with lupus including, but not limited to, addressing social determinants of health, access to health care resources, outcomes research, patient-reported outcomes, symptom and disease control, comparative effectiveness research, maternal fetal health and issues and challenges that, when addressed, make day-to-day living with lupus easier and life more fulfilling
• Understanding the underlying genetic and epigenetic components and gene - environment interactions of lupus and how they may relate to clinical disease characteristics, variations, disparities, and differences in response to therapies using functional genomic studies
• Innovative health care delivery models improving outcomes for lupus
Independent investigators at or above the level of Assistant Professor (or equivalent) are eligible to be named by the applicant organization as the PI. Each investigator may be named on only one FY23 LRP Impact Award application as a PI.
The anticipated total costs budgeted for the entire period of performance for an FY23 LRP Impact Award should not exceed $1,000,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.
