The MBRP CTRA is intended to support the rapid implementation of clinical research (including clinical trials) with the potential to significantly impact burn care by applying promising and well-founded research findings to the care of the burn-injured patient, particularly at the point-ofinjury, or during the early, acute phase of burn injury.
Impact: The overall impact of the proposed research is a key component of this award mechanism. The potential impact of the research, both short-term and long-term, in addressing one or more of the FY22 MBRP Focus Areas should be clearly described. High-impact clinical research will, if successful, significantly advance the burn research field and the care of burninjured patients. To be competitive, the application must include a sound scientific rationale, logical reasoning, and a well-formulated, testable hypothesis.
Relevance to Military Health: The proposed research must be relevant to Service Members, Veterans, military beneficiaries, and/or the American public. Investigators are encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health: • Explanation of how the project addresses an aspect of burn injuries relevant to the military • Description of how the results of the proposed research will address a military need
Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique data and research resources that the partners bring to the research effort, ultimately advancing burn research which is of significance to the Service Member, military families, and the American public.
Deadlines:
• Pre-Application Deadline: June 27, 2022
• Invitation to Submit an Application: Aug. 2022
• Application Submission Deadline: Oct. 11, 2022
In order to meet the MBRP mission “to identify and address gaps in burn trauma care through military focused research,” the program seeks to fund research that enhances the ability to prevent burn complications, assess burn injuries, and/or treat burns and burn-associated complications which ultimately facilitates the improvement of health and performance outcomes of burn-injured Service Members, Veterans, military beneficiaries, and/or the American public. Within this context, the MBRP is interested in research proposals that address specific gaps in the area of military-relevant burns; therefore, the proposed research must address at least one of the following FY22 MBRP Focus Areas:
• Atypical Burns: Development and/or validation of methods to prevent, triage, and/or treat burns resulting from exposure to cold, radiation, directed energy, or high voltage (especially military duty-related) electrical injuries. Novel interventions that focus on technology or therapeutics other than topical agents or dressings are of particular interest.
• Burn Injury During Mass Casualty: Development and/or validation of methods/techniques to improve triage, delivery of care, or capacity capabilities after burn mass casualty events. Methods/techniques must be specific to events where large numbers of burn casualties are expected.
• Burn Injury-Related Complications: Development and/or validation of methods to prevent, assess, and/or treat burn injury related complications. Studies must address at least one of the following burn injury complications: ○ Over/under fluid resuscitation to include limited- or low-volume resuscitation ○ Acute Respiratory Distress Syndrome ○ Sepsis ○ Inhalation injuries
PIs at or above the level of Assistant Professor (or equivalent) may be named by the organization as the PI on the application. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by, or affiliated with, an eligible organization.
The anticipated total costs budgeted for the entire period of performance for an FY22 MBRP CTRA Award will not exceed $2.21M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.
