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Congressionally Directed Medical Research Programs -- Parkinson’s Research Program -- Focused Idea Award
The PRP Focused Idea Award mechanism is being offered for the first time in FY16.
The Focused Idea Award is intended to support projects that have the potential to yield high-impact findings and new avenues of investigation. This award mechanism supports conceptually innovative research that could lead to critical discoveries in Parkinson’s disease research and/or patient care. The critical components of this award mechanism are:
- Impact: The Focused Idea Award is intended to support research that demonstrates the potential to have a major impact on an area of paramount importance in Parkinson’s disease. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly describe the potential impact of the proposed study on Parkinson’s disease and to convey its level of significance. The research impact is intended to benefit individuals with Parkinson’s disease including Service members and Veterans by slowing the progression of, preventing, and/or curing Parkinson’s disease.
- Principal Investigator and Research Team: The FY16 PRP Focused Idea Award seeks applications from investigators from a spectrum of disciplines including, but not limited to, basic science, engineering, bioinformatics, population science, translational research, and clinical research. The application should demonstrate that the research team’s background is appropriate to successfully achieve the proposed research and contribute to the field of Parkinson’s disease research.
- Focus Area: The proposed research MUST address at least one of the FY16 PRP Focused Idea Award Focus Areas.
- Research Approach: The scientific rationale and experimental methodology should demonstrate critical understanding and in-depth analysis of Parkinson’s disease. Experimental strategies may be novel or may be based on strong rationale derived from previously published data, presented preliminary data, or literature review. The feasibility of the research design and methods should be well defined, and a clear plan should be articulated as to how the proposed goals of the project can be achieved.
- Preliminary data are not required. However, if unpublished preliminary data are provided, they should originate from the laboratory of the PI or a member(s) of the research team and support the feasibility of the study.
- Pre-Application Submission Deadline: November 9, 2016
- Application Submission Deadline: November 30, 2016
Areas of Interest
All applications to the FY16 PRP Focused Idea Award Program Announcement/Funding Opportunity MUST address at least one of the following FY16 PRP Focused Idea Award Focus Areas:
- Studies of the neurovascular unit (including neurons, glia, the microvasculature, and the blood-brain barrier) in Parkinson’s disease and changes associated with its treatment.
- Identification and evaluation of mechanisms in early Parkinson’s disease involving olfactory, microbiome, gastrointestinal, and/or autonomic nervous systems.
- Mechanisms of neuroplasticity and compensation in Parkinson’s disease, such as influences of sleep, exercise, and diet.
Independent investigators at or above the level of Assistant Professor (or equivalent) are eligible to submit an application.
- The maximum period of performance is 3 years.
- The anticipated direct costs budgeted for the entire period of performance will not exceed $350,000. Indirect costs are to be budgeted in accordance with the organization’s negotiated rate. No budget will be approved by the Government exceeding $350,000 direct costs or using an indirect rate exceeding the organization’s negotiated rate.
- All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.
- The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 3 years.