Congressionally Directed Medical Research Programs -- Parkinson’s Research Program -- Impact Award -- Deadline Extended

Funding Agency:
Department of Defense

The PRP Impact Award mechanism is being offered for the first time in FY16.

The Impact Award encourages applications that support the full spectrum of research projects or ideas that specifically focus on scientific and clinical Parkinson’s disease issues, which, if successfully addressed, have the potential to make a major impact in preventing or halting the progression of Parkinson’s disease or enhancing the well-being of individuals experiencing the impact of the disease. 

The PRP seeks applications from investigators from a spectrum of disciplines including, but not limited to, basic science, engineering, bioinformatics, population science, translational research, and clinical research, NOT including clinical trials. Projects that incorporate population sciencebased approaches are particularly encouraged. 


  • Pre-Application (Letter of Intent) Submission Deadline: November 9, 2016 (was Sep. 7, 2016)
  • Application Submission Deadline:  November 30, 2016

Agency Website

Areas of Interest

All applications to the FY16 PRP Impact Award Program Announcement/Funding Opportunity MUST address at least one of the following FY16 PRP Impact Award Focus Areas:

  • Studies of the neurovascular unit (including neurons, glia, the microvasculature, and the blood-brain barrier) in Parkinson’s disease and changes associated with its treatment.
  • Identification and evaluation of mechanisms in early Parkinson’s disease involving olfactory, microbiome, gastrointestinal, and/or autonomic nervous systems.
  • Mechanisms of neuroplasticity and compensation in Parkinson’s disease, such as influences of sleep, exercise, and diet.
  • Underlying factors influencing Parkinson’s disease progression in specific communitybased populations (e.g., Veterans) to identify heterogeneity. 

Eligibility Requirements

Independent investigators at or above the level of Assistant Professor (or equivalent) are eligible to submit an application. 



Amount Description

Single PI:

  • The maximum period of performance is 4 years.
  • The anticipated total costs (direct and indirect) budgeted for the entire period of performance will not exceed $3M. Indirect costs are to be budgeted in accordance with the organization’s negotiated rate. No budget will be approved by the Government exceeding $3M total costs or using an indirect rate exceeding the organization’s negotiated rate.

Partnering PI Option:

  • The maximum period of performance is 4 years.
  • The anticipated combined total costs budgeted for the entire period of performance for the Initiating PI and the Partnering PI’s/PIs’ applications will not exceed $5M. The combined total costs of Initiating PI and the Partnering PI’s/PIs’ awards will not exceed $5M. If the Initiating PI’s or Partnering PI’s/PIs’ budgets contain a subaward (or multiple subawards), all costs of the subaward(s) must be included in the total costs of the primary award. Collaborating organizations should budget associated indirect costs in accordance with each organization’s negotiated rate. The combined budgeted total costs (direct and indirect) approved by the Government will not exceed $5M or use an indirect rate exceeding each organization’s negotiated rate.
  • A separate award will be made to each PI’s organization.
  • The PIs are expected to be partners in the research, and direct cost funding should be divided accordingly, unless otherwise warranted and clearly justified.

For both the Single PI and the Partnering PI Option:

  • All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.
  • The applicant(s) may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 4 years. 

Funding Type



Junior Faculty


Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

November 9, 2016