The PRP SIA supports new ideas that represent synergistic approaches to PD research involving two to four Principal Investigators (PIs) at the Assistant Professor (or equivalent) level or above. These investigators should utilize their complementary and synergistic perspectives to address a central problem or question in Parkinson’s research. This award is designed to support both new and pre-existing partnerships and encourages participation of PIs from other research fields. The PRP Synergistic Idea Award seeks applications from investigators working in a wide spectrum of disciplines including, but not limited to, basic science, engineering, bioinformatics, population science, translational research, and clinical research.
The PRP SIA requires more than one PI. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. All PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. If recommended for funding, each PI will be named to an individual award within the recipient organization. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission.
Deadlines:
All applications to the FY23 PRP Synergistic Idea Award (SIA) program announcement MUST address at least one of the following FY23 PRP Focus Areas:
• Biological mechanisms or biomarkers, including biologically informed clinical evaluations, of non-motor symptoms that could lead to the development of treatments for PD. Applications focused on laboratory models through to human subjects, including computational approaches, would be considered. Examples of non-motor symptoms of interest include, but are not limited to: ○ Cognitive dysfunction relevant to PD ○ Psychiatric dysfunction ○ Sleep and circadian rhythms disruptions ○ Autonomic dysfunction ○ Sensory dysfunction ○ Other non-motor symptoms including fatigue, apathy, and impulse control disorders
• Biological mechanisms or biomarkers associated with non-pharmacological interventions for PD. Examples of non-pharmacological interventions of interest include: ○ Exercise ○ Diet ○ Neuro-stimulation therapy ○ Neurosurgical
Investigators must be at or above the level of Assistant Professor (or equivalent) to be named as the Initiating or Partnering PI on the application. An investigator may be named on only one PRP SIA application as an Initiating or Partnering PI. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by or affiliated with an eligible organization.
The anticipated total costs budgeted for the entire period of performance for an FY23 Synergistic Idea Award should not exceed $3M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.
