Congressionally Directed Medical Research Programs -- Peer Reviewed Alzheimer’s Disease Research Program -- Quality of Life Research Award

Funding Agency:
Department of Defense

The PRARP Quality of Life Research Award (QUAL) mechanism was first offered in FY13. Since then, 38 QUAL applications have been received, and 16 have been recommended for funding.

The intent of the research funded through this award is to (1) support research to alleviate, stabilize, or characterize the symptoms or deficits common to TBI and AD/ADRD, and (2) reduce the burden of care on the caregiver for individuals living with the common symptoms of TBI and AD/ADRD. Research may be proposed to either facet of the intent. Both are equally important. As part of the research strategy, all applications must include cognitive, neuropsychological, or otherwise appropriate measures. 

The FY17 PRARP QUAL is open to Principal Investigators (PIs) at or above the level of Assistant Professor (or equivalent) from any field or discipline. As part of the application, the PI should demonstrate that the study team has experience in both TBI and AD/ADRD research. 

Deadlines:

  • REQUIRED Pre-application Submission Deadline:  September 21, 2017 (was September 6, 2017)
  • Full Application Submission Deadline:  October 5, 2017 (was September 20, 2017)

Agency Website

Areas of Interest

​FY17 PRARP QUAL Overarching Challenges: This FY17 PRARP QUAL funding opportunity requires applications to address one or more of the following Overarching Challenges:

• Paucity of Clinical Studies: The paucity of clinical studies to examine the interrelationship between TBI and subsequent AD/ADRD for the military, Veteran, and civilian communities. This includes research into risk factors that may predispose individuals to AD/ADRD subsequent to TBI.

• Epidemiology: The paucity of epidemiological research to examine the interrelationship between TBI and subsequent AD/ADRD for the military, Veteran, and civilian communities. This includes research into risk factors that may predispose individuals to AD/ADRD subsequent to TBI.

• Quality of Life: The need for technologies, assessments, interventions, or devices to benefit individuals living with the common symptoms of TBI and AD/ADRD.

• Caregiver Burden: The need for technologies, assessments, interventions, or devices with the goal of reducing burden for caregivers of individuals living with the symptoms of TBI and AD/ADRD.

FY17 PRARP QUAL Focus Areas: In addition to addressing one or more of the specified FY17 PRARP QUAL Overarching Challenges, applications should address at least one of the following FY17 PRARP QUAL Focus Areas in support of the FY17 PRARP QUAL Overarching Challenges. An application that proposes research outside of these FY17 PRARP QUAL Focus Areas is acceptable, as long as the applicant provides a strong rationale:

• Quality of Life: Research intended to alleviate, stabilize, or characterize the symptoms, or deficits, common to TBI, AD/ADRD. Examples of research in this Focus Area include identification and management of comorbidities and modifiable risk factors (e.g., sleep apnea, obesity); cognitive training interventions; studies of health and wellness and behavioral interventions. 

• Caregiver Support: Research intended to reduce the burden of care on the caregiver for individuals living with the common symptoms or deficits of TBI and AD/ADRD. Examples of research in this focus area include: caregiver training, home-based support, behavioral interventions, and relationship interventions.

• Biomarkers: Development of strategies to diagnose, prognose, or characterize neurological changes or risk factors associated with TBI and subsequent AD/ADRD (e.g., fluid-based, imaging, physiological, and clinical approaches).

• Epidemiological Research: Research focusing on the incidence, distribution, and other factors relating to the health of individuals affected by TBI and subsequent AD/ADRD.

Eligibility Requirements

The PI must be an independent investigator at or above the level of Assistant Professor (or equivalent). 

Amount

$500,000

Amount Description

The anticipated direct costs budgeted for the entire period of performance for an FY17 PRARP QUAL will not exceed $500,000. The maximum period of performance is 3 years. Refer to Section II.D.5, Funding Restrictions, for detailed funding information. 

Funding Type

Grant

Eligibility

Faculty
Junior Faculty

Category

Interdisciplinary
Medical
Medical - Basic Science
Medical - Clinical Science
Social Sciences

External Deadline

September 21, 2017