Congressionally Directed Medical Research Programs -- Peer Reviewed Alzheimer’s Disease Research Program -- Leveraging Approaches for Innovation in Care and Support Award

Funding Agency:
Department of Defense

The intent of the FY21 PRARP LEAP-InCASA is to support innovative and impactful research that improves the quality of life and care for individuals, families, and care providers living with AD/ADRD. The proposed work should innovatively challenge existing research paradigms or exhibit high levels of creativity within the context of the PRARP’s mission and vision. This can include innovations and research for symptom reduction (e.g., cognitive, behavioral, function, mood), resiliency factors, increasing or maintaining independence, and support for families and care providers.

The FY21 PRARP LEAP-InCASA supports multi-institutional, harmonized research initiatives. As such, applications to the FY21 PRARP LEAP-InCASA require a Coordinating Center and a minimum of two Partnering Sites, representing at least three separate institutions within the application package. While the Coordinating Center provides overall infrastructure and support, each Partnering Site should develop its own unique research initiative that will be part of the overall project. The application should also demonstrate the study team’s experience in both military risk factor-related research and AD/ADRD as suited to the proposed work. Given the patient-centered intent of the FY21 PRARP LEAP-InCASA, animal research is prohibited.


  • REQUIRED Pre-application Submission Deadline:  June 14, 2021
  • Full Application Submission Deadline:  July 21, 2021

Agency Website

Areas of Interest

FY21 PRARP LEAP-InCASA Overarching Challenges: The Overarching Challenges below are specific to the FY21 PRARP LEAP-InCASA. Applicants to the FY21 PRARP LEAPInCASA must address and select one of the Overarching Challenges below:

• Quality of Life: The need for technologies, assessments, interventions, or devices to benefit individuals, especially Service Members and Veterans living with symptoms of AD/ADRD.

• Family and Care Support: The need for technologies, assessments, interventions, or devices that enhance the lives of those providing care and families of individuals, especially Service Members, living with the symptoms of AD/ADRD.

Eligibility Requirements

The Coordinating Center PI must be at or above the level of assistant professor (or equivalent) at the time of the application submission deadline.

Each named Partnering Site PI must be at or above the level of assistant professor (or equivalent) at the time of the application submission deadline.

Each investigator may be named on only one FY21 PRARP LEAP-InCASA application as a PI.



Amount Description

The anticipated total costs budgeted for the entire period of performance for an FY21 PRARP LEAP-InCASA will not exceed $2,800,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

Funding Type



Junior Faculty


Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

June 14, 2021