Congressionally Directed Medical Research Programs -- Peer Reviewed Alzheimer’s Research Program -- Transforming Diagnosis Award

Funding Agency:
Department of Defense

The TrDA is intended to improve diagnosis now. Proposed projects must build knowledge, capacity, technology, and/or research to reduce or overcome important barriers to obtaining a diagnosis, meaningful disease monitoring, and accurate prognosis. Barriers could include, but are not limited to, technologies, cost, equitable patient access, applicability, structural and social determinants of health, clinical implementation, relationship to clinical outcome measures, biomarker validation, lack of longitudinal data to inform prediction/prognosis, and more. The investigator must clearly attune their project to provide true benefit to people living with AD/ADRD diagnoses and their families.

All applications submitted to this funding opportunity must clearly indicate how the project addresses an important barrier, explain how the research will be representative of the population it intends to benefit, and demonstrate cultural competence. Culturally competent research factors the cultural background and diversity of the intended beneficiaries of the research outcomes when developing research ideas, conducting research, and implementing the research findings. Cultural competency in research is critical in reducing health disparities and enhancing the quality and impact of research by ensuring inclusivity, understanding, and responsiveness to the needs of diverse populations.


• Pre-Application Submission Deadline: May 22, 2024

• Application Submission Deadline:  June 20, 2024

Agency Website

Eligibility Requirements

Independent investigators at all career levels may be named by the organization as the PI on the application.

Career Initiation or Transition Partnering PI Option: CIT investigators should have nominal, if any, research support. Career initiation investigators must have at least 3 years research experience beyond a terminal degree but no more than 7 years within their first independent research position. Career transition investigators may be any level, but new to military, TBI, and/or AD/ADRD fields, with nominal, if any, publications for their intended field. Lapses in research time or appointments as denoted in the biographical sketch should be explained in the application.



Amount Description

The anticipated total costs budgeted for the entire period of performance for an FY24 PRARP TrDA should not exceed $2.0M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

Funding Type



Junior Faculty
Post Doctoral Fellows


Medical - Clinical Science
Medical - Translational

External Deadline

May 22, 2024