The Mission of the FY22 PCRP is to fund research that will lead to the elimination of death from prostate cancer and enhance the well-being of Service Members, Veterans, and all the men and their families who are experiencing the impact of the disease. Within this context, the PCRP is interested in supporting research that addresses specific gaps in prostate cancer research and clinical care; therefore, applications are required to address one or more of the following FY22 PCRP Overarching Challenges:
• Improve quality of life to enhance outcomes and overall health and wellness for those impacted by prostate cancer
• Develop treatments that improve outcomes for men with lethal prostate cancer
• Advance health equity and reduce disparities in prostate cancer
• Define the biology of prostate cancer progression to lethal prostate cancer to reduce death
The PCRP is interested in research that addresses all different aspects that contribute to health disparity in prostate cancer. The Focus Areas outlined below broadly describe the primary areas that may contribute to disparities in prostate cancer incidence, morbidity, mortality, and survivorship:
- Biological contributors, such as genetic and genomic differences, that can be associated with disparate outcomes in patient populations.
- Environmental factors that may cause endogenous changes, such as environmental exposures, dietary factors, lifestyle factor, and other external factors that may contribute to prostate cancer disparities in specific populations.
- Social and cultural factors that may influence decision-making of patients, their family, or caregiver as it relates to the screening and treatment of prostate cancer, such as the role of social/support networks, community influence, cultural or religious practices, and psychological health.
- Access to health care, which may stem from geographic location, socioeconomic status, or other factors.
Each investigator may be named on only one FY22 Health Disparity Research Award application as a PI.
Although a PI may be eligible for both the Established Investigator and New Investigator categories, only one category may be chosen; the choice of application category is at the applicant’s discretion.
- The PI must be an independent investigator at or above the level of Assistant Professor (or equivalent).
New Investigator: By the application submission deadline, the PI must have:
○ The freedom to pursue independent research goals without formal mentorship; ○ Not previously received a PCRP Health Disparity Research Award and/or Idea Development Award;
○ The PI must be an independent, early-career investigator within 10 years after completion of his/her terminal degree by the time of the application submission deadline (excluding time spent in residency or on family medical leave). Time spent as a postdoctoral fellow is not excluded. Lapses in research time or appointments as denoted in the biographical sketch may be articulated in the application.
○ New Investigators working under another investigator are eligible to apply for this award provided they can demonstrate that they have the freedom to pursue independent research goals without formal mentorship. Graduate students and junior postdoctoral fellows (i.e., fellows with less than 3 years of postdoctoral training by the application submission deadline) are not eligible to apply as a New Investigator.
The anticipated direct costs budgeted for the entire period of performance for an FY22 PCRP Health Disparity Research Award will not exceed $900,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.