Congressionally Directed Medical Research Programs -- Toxic Exposures Research Program -- Investigator-Initiated Research Award

Funding Agency:
Department of Defense

The FY22 TERP IIRA is intended to support studies that will make an important contribution toward research and/or patient care for a disease or condition related to toxic exposures. Research projects may focus on any phase of research from basic laboratory research through translational research, including preclinical studies in animal models and human subjects, as well as correlative studies associated with an existing clinical trial. New Approach Methodologies may also be used.

Impact: The application should explicitly state how the proposed research will have a significant impact on toxic exposure research and/or patient care with the intent to transition outcomes into clinical practice for Service Members, Veterans, and/or the American public who have been, or could potentially be, impacted by toxic exposures. State both the short- and longterm impacts and how the proposed research will ultimately lead to new treatments/therapeutics, diagnostic assays, or prevention strategies to improve the quality of life for those that have been impacted by, or are likely to encounter, toxic substances.


• Required Pre-Application Submission Deadline: November 3, 2022

• Application Submission Deadline:  December 1, 2022

Agency Website

Areas of Interest

Climate and health

Eligibility Requirements

Independent intramural (DOD) and extramural investigators at all academic levels (or equivalent) may be named by organizations as the Principal Investigator (PI) on the application.

Amount Description

The anticipated direct costs budgeted for the entire period of performance for an FY22 TERP IIRA will not exceed $500,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

Funding Type



Junior Faculty


Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

November 3, 2022