Consortium on Translational Research in Early Detection of Liver Cancer: Data Management and Coordinating Center (U24 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) is a part of an initiative designed to establish a Liver Cancer Consortium to advance translational research focused on early detection of liver cancer. The Consortium will consist of a Data Management and Coordinating Center (DMCC, to be supported by this U24 FOA) and several Translational Research Centers (TRCs, to be supported by the companion U01 FOA, RFA-CA-22-031).

The DMCC will support the TRCs and coordinate trans-Consortium activities with the following specific responsibilities:

  1. (1) Overall administrative and logistical coordination for the Liver Cancer Consortium;
  2. (2) Support for Consortium collaborative research studies and biospecimen collections, including protocol development, data processing, statistical support, and computational analysis; and
  3. (3) Consortium data management, including developing and maintaining an integrated database of research data generated by the consortium, as well as management of all data relevant to biospecimens used in TRC studies (including clinical data annotations, and specimen usage tracking).

To achieve these goals, the DMCC is expected to provide multi-disciplinary expertise in liver cancer research, biomarkers for cancer detection, biostatistics, bioinformatics, and the information technology infrastructure to support data management for the Consortium.


  • Letter of Intent Due Date(s): October 7, 2022

  • Application Due Date: November 07, 2022

RFA-CA-22-032 Expiration Date November 08, 2022

Agency Website

Eligibility Requirements

The FOA will be open to all qualified applicants, including new and early-stage investigators, who can establish and lead a Coordinating Center project. A multi-PI collaboration that can bring a new scientific expertise to program coordination is particularly encouraged.



Amount Description

Application budgets should not exceed $400,000 in direct costs and need to reflect the actual needs of the proposed project.

A project period of 5 years is required.

Funding Type





Medical - Clinical Science
Medical - Translational

External Deadline

November 7, 2022