Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network (UG1)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites applications to participate as a Core Clinical Center/Consortia in the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). This collaborative multi-center clinical program promotes the efficient comparison of novel treatment approaches and management strategies for potential benefit of children and adults undergoing hematopoietic stem cell transplantation (HCT), either alone or in combination with novel cell-based therapies. Collaboration among the Core Clinical Centers, the Data Coordinating Center, the NHLBI, the NCI, and other stakeholders will permit multi-center evaluation of new HCT approaches with attention to treatment of malignant and non-malignant blood diseases. During this funding cycle, the BMT CTN will have the flexibility to conduct early phase multi-center HCT trials incorporating novel cell therapies, and to expand the use of promising products from highly selected to more heterogeneous patient populations. The overall goals of the BMT CTN are to improve HCT outcomes, evaluate promising novel cell therapies, and rapidly disseminate study results to improve the scientific basis for the treatment of patients in need of HCT therapy.

There is a separate Funding Opportunity Announcement (FOA) for the BMT CTN Data Coordinating Center (RFA-HL-17-019). 


  • Letter of Intent Due Date(s): October 10, 2016
  • Application Due Date(s): November 10, 2016

​RFA-HL-17-018 Expiration Date November 11, 2016

Agency Website

Eligibility Requirements

Eligibility is limited to current awardees of the NHLBI-funded BMT Data Coordinating Center award (RFA-HL-11-028).



Amount Description

Application budgets may not exceed direct costs of $120,000 per year in fiscal years 2017 through 2023 to support research infrastructure.  Protocol budgets should be commensurate with the scope and complexity of the protocol.

The maximum project period is seven years.     

Funding Type





Medical - Basic Science
Medical - Clinical Science

External Deadline

November 10, 2016