Crazy 8 Initiative Award

Funding Agency:
Alexs Lemonade Stand Foundation

Crazy 8 Initiative Awards may involve the exploration of a novel scientific hypothesis or the development of new model systems, tools or technologies that have the potential for significant impact on the field of childhood cancer research. We expect successful applications to propose multidisciplinary teams with a clear plan for collaboration, which would empower the study of big ideas that would not be easily addressable otherwise. Childhood cancer research applicants are encouraged to bring new, necessary expertise into the field.


The budget for this award is between $3-5 million USD over four years, and funding is set to begin in Q1 of 2022. To learn more about the Crazy 8 Initiative 2021 funding priorities and the full program description, read the award guidelines here.


A Letter of Intent is due April 26, 2021. If selected, researchers will be asked to submit a full application by August 5, 2021. Chosen finalists will present during the time frame of December 8-10, 2021 at a virtual Crazy 8 meeting.


Agency Website

Areas of Interest

Crazy 8 Disciplines 1. Embryonal brain cancers 2. High grade gliomas 3. Fusion positive sarcomas 4. Fusion negative sarcomas 5. Leukemias 6. Neuroblastoma 7. Big data 8. Catalyzing clinical trials 

Eligibility Requirements

• Applicants must have an MD, PhD, or MD/PhD or equivalent and be appointed as faculty (or equivalent) at an academic institution. • Applicants must have a track record of publication and funding productivity that should demonstrate that the project can be accomplished by the investigators. • Applicant institutions may be based in the United States or abroad, and applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations. 

Amount Description

The requested budget should be in proportion to the scope of the proposed project and its corresponding potential for impact. Depending on the type of project and the size of the team, the requested budget should be in the range of $1-5 million USD over 4 years.

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

April 26, 2021