Dementia Care and Caregiver Support Interventions (R01 - Clinical Trial Required)

Funding Agency:
National Institutes of Health

The overarching purpose of this FOA is to help to lay the groundwork for pragmatic trials and real-world implementation of Alzheimer's disease (AD) and AD-related dementias (ADRD) care and caregiving interventions by supporting early-Stage (Stage I, II, III of the NIH Stage Model) behavioral intervention development clinical trials aimed at adapting/modifying interventions for the real world, examining the principles underlying these interventions, developing methods to ensure real-world fidelity of delivery, and developing training procedures for the people in the community who will be delivering the interventions. 

AD/ADRD care and caregiver support intervention research can be for implementation in the home, community, or formal care settings, such as nursing homes, assisted living facilities, nursing and rehabilitation centers, hospitals, adult day care, and specialized hospice settings. These interventions may target behavioral, psychological, interpersonal, social, or institutional processes and may be designed for use at the individual, family, dyad, group, community, or health systems level. Applications may propose intervention research for any stage of AD/ADRD. Applications addressing care needs and challenges for individuals from diverse racial, ethnic, and socioeconomic backgrounds are strongly encouraged. Applicants should specify the disease stage(s), the setting/context, and the population being studied. Applications that involve interdisciplinary expertise and translational expertise (e.g., basic science expertise as appropriate regarding questions about mechanisms, implementation expertise as appropriate when designing real-world friendly interventions) are strongly encouraged. Applications proposing to create, modify, and test AD/ADRD care and caregiver support interventions are encouraged, as appropriate, to incorporate the NIH Science of Behavior Change (SOBC) experimental medicine approach.   


  • Letter of Intent Due Date(s): March 10, 2018
  • Application Due Date(s): April 10, 2018

RFA-AG-18-030 Expiration Date April 11, 2018

Agency Website

Eligibility Requirements

Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity.



Amount Description

 No more than $350,000 in direct costs may be requested in any single year. Application budgets need to reflect the actual needs of the proposed project.

The scope of the proposed project should determine the project period. The maximum project period is 5 years.   

      Funding Type





      Medical - Clinical Science
      Social Sciences

      External Deadline

      April 10, 2018