Demonstration Projects to Research and Evaluate Strategies Aligned with CDC’s What Works in Schools Approach

Funding Agency:
Centers for Disease Control and Prevention

This Notice of Funding Opportunity (NOFO) supports research to implement and evaluate strategies aligned with CDC’s What Works in Schools (WWIS) approach for successful implementation in local education agencies and schools serving rural or American Indian and/or Alaska Native (AI/AN) adolescents to address students’ health behaviors, experiences, and outcomes, particularly those related to sexual and reproductive health and mental and behavioral health, as well as suicidality, substance use, and experiences of violence. The purpose of the research is to build the evidence base for innovative, school-based or school-linked strategies that promote the health of youth across multiple health domains while also supporting translation and dissemination of the research findings. Strategies may include programs, policies, or practices that seek to improve sexual and reproductive health as well as improve mental and behavioral health in a manner that also addresses health equity among youth in local education agencies and schools serving rural or AI/AN adolescents. Additionally, strategies may also seek to reduce suicidality, substance use and experiences of violence among school-aged adolescents.

Only one application per institution (normally identified by having a unique UEI number) is allowed. Interested applicants from within Duke should contact as early as possible.

Deadline: March 11, 2024

Agency Website

Amount Description

The estimated total funding (direct and indirect) for the first year (12-month budget period) will be $1,000,000.00 with individual awards of $500,000.00 each for two awards. The estimated total funding (direct and indirect) for the entire project period will be $5,000,000.00. The project period is anticipated to run from 09/29/2024 to 09/28/2029.

Funding Type





Community Outreach and Engagement
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

March 11, 2024