Duke Specialized Program in Research Excellence (SPORE) in Brain Cancer Career Enhancement Program

Funding Agency:
Duke University

The National Cancer Institute-funded SPORE in Brain Cancer at Duke University is requesting applications for pilot projects from new and early stage investigators with translational1 potential for funding through the SPORE Career Enhancement Program (CEP).

The CEP of the Duke University SPORE in Brain Cancer supports promising individual or collaborative pilot research projects that have a translational potential and are likely to generate new knowledge with a high probability to impact the diagnosis, treatment and/or prevention of adult and/or pediatric brain tumors. In accordance with NIH provisions, all funded CEP projects that have strong translational potential may become full projects in the SPORE. Although both clinical and laboratory research projects are eligible for funding, the translational emphasis of the program requires that the hypotheses in all projects have the potential to impact the incidence and mortality of brain cancer or improve the quality of life for brain cancer patients. These projects, however, do not have to reach a human endpoint during the project period, but should, ideally, utilize human cells or tissues, and/or, have the potential to translate to the human context. The resources of the Duke SPORE in Brain Cancer, including the SPORE Biospecimen, Pathology, and Immune Monitoring Core, are available to all investigators and those interested in utilizing these resources should consult with the appropriate Core leaders. Innovative projects are encouraged. We particularly wish to encourage women and minority investigators, investigators from minority and other area institutions, as well as individuals who have not previously worked in the brain tumor field to apply. Applications for scientific teams and scientists exploring new areas of investigation are encouraged. Duke is an equal-opportunity employer, and we value diversity in all of its many facets and meanings.

Stage 1 deadline for all applications is by noon on June 10, 2022. Late applications will not be accepted. All applications will be submitted electronically to Steve Keir, DrPH, MPH, MMCi, Scientific Administrator, at stephen.keir@duke.edu.

Full RFA

Agency Website

Eligibility Requirements

This program typically supports junior faculty or established investigators who wish to further develop or refocus their careers on translational research in primary brain cancer. This program does not support pre- or post-doctoral fellows, either preclinical or clinical. However, advanced post-doctoral or clinical fellows who provide a letter from an institution stating that the candidate will be joining its faculty within the year are eligible for this program. Investigators supported by NCI career development awards (K series) may also be eligible for support through this program. An applicant should not have previously received funding through the Duke Brain SPORE CEP.

Current recipients of an award from the Brain SPORE CEP may submit a competitive renewal application for a second year of funding. This will be contingent upon productivity and successful completion of the work during the first-year award. In addition to the criteria outlined for new applicants, competitive renewal applications should include a progress report and a description of the proposed work to be accomplished in the second year.



Amount Description

Funding decisions will be made in August and communicated directly to the PI. Successful projects will be funded September 1, 2022 - August 31, 2023, at a maximum of $100,000 per year, renewable for a second year.

Funding Type



Junior Faculty
Women and minorities encouraged


Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

June 10, 2022