Duke Specialized Program in Research Excellence (SPORE) in Brain Cancer Developmental Research Program

Funding Agency:
Duke University

The National Cancer Institute–funded SPORE in Brain Cancer at Duke University is requesting applications for pilot projects for funding through the SPORE Developmental Research Program (DRP).

The DRP of the Duke University SPORE in Brain Cancer supports promising individual or collaborative pilot research projects that have a translational1 potential and are likely to generate new knowledge with a high probability to impact the diagnosis, treatment and/or prevention of adult and/or pediatric brain tumors. In accordance with NIH provisions, all funded DRP projects that have strong translational potential may become full projects in the SPORE. Although both clinical and laboratory research projects are eligible for funding, the translational emphasis of the program requires that the hypotheses in all projects have the potential to impact the incidence and mortality of brain cancer or improve the quality of life for primary brain cancer patients. These projects, however, do not have to reach a human endpoint during the funding period, but should, ideally, utilize human cells or tissues, and/or, have the potential to translate to the human context. The resources of the Duke SPORE in Brain Cancer, including the SPORE Biospecimen, Pathology, and Immune Monitoring Core, are available to all investigators and those interested in utilizing these resources should consult with the appropriate Core leaders. Innovative, high risk / high gain projects are encouraged. We particularly encourage women and minority investigators, investigators from minority and other area institutions, as well as individuals who have not previously worked in the brain tumor field to apply. Applications for scientific teams and scientists exploring new areas of investigation are encouraged. Duke is an equal-opportunity employer, and we value diversity in all of its many facets and meanings.

Deadline: June 9, 2023

Full RFA

Eligibility Requirements

Applicant(s) must hold a faculty or equivalent position at Duke University or at their institutions, universities, or research organizations at the time of the application.
Current recipients of an award from the Duke Brain SPORE DRP may submit a competitive renewal application for a second year of funding. This will be contingent upon productivity and successful completion of the work during the first-year award. In addition to the criteria outlined for new applicants, competitive renewal applications should include a progress report and a description of the proposed work to be accomplished in the second year.



Amount Description

Each selected project will be funded at $50,000 to $100,000 per year for a minimum of one year, renewable for a maximum of two years. Funding decisions will be made in August and communicated directly to the Principal Investigator. The project period will be September 1, 2023–August 31, 2024.

Funding Type



Junior Faculty
Women and minorities encouraged


Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

June 9, 2023