Duke/RTI Collaborative Translational Research Grants - Request for Applications

Funding Agency:
Duke University

This pilot program is designed to facilitate novel clinical and translational research that applies or accelerates discovery into testing in clinical or population settings. Projects will advance solutions by applying discoveries generated during research in the laboratory, and in preclinical studies in the areas of medicinal chemistry, computational chemistry, High Throughput Screening (HTS) and assay development, in vitro absorption–distribution–metabolism–excretion–toxicity (ADMET) and pharmacology and in vivo pharmacokinetics in clinical or population settings.

The Duke Clinical and Translational Science Institute (Duke CTSI) is the academic home of the National Institutes of Health’s Clinical and Translational Science Awards (CTSA) pilot funding programs at Duke University, is partnering with RTI International (RTI) to support new inter-institutional collaborative research teams. 

Duke CTSI and RTI are interested in the following types of translational research projects that foster collaboration between the two institutions:

  • Research that generates translational discoveries relevant to human health or disease, regardless of whether the context of the discovery is the laboratory, in animal models or the field.
  • Research that applies or accelerates discovery into testing in clinical or population settings.

Deadline for Mandatory Letter of Intent (LOI): May 21, 2021

Agency Website

Eligibility Requirements

  • Proposed projects must involve a lead investigator from Duke (full-faculty appointment) and a lead investigator from RTI. Proposals are encouraged from new teams of investigators from different disciplines.  An RTI investigator will be identified to collaborate on invited applications following the LOI presentation.
  • More than one proposal may be submitted by a Duke Faculty member acting as PI, but the Duke Faculty member is only eligible to receive one award as PI from this funding mechanism during a given funding cycle.
  • Submission of mandatory LOI (see section VII. For submission instructions).
  • Completion of proposal presentation to CTSI and RTI for selected LOI applicants. Upon conclusion of the presentation you will be connected with a RTI investigator to collaborate on Full Application Submission, if invited.



Amount Description

The research activities at each participating institution will be funded by the Duke CTSI and RTI.  The Duke CTSI and RTI will fund up to $50,000 per award ($25,000 per institution).

Funding Type



Junior Faculty


Medical - Translational

External Deadline

May 21, 2021