The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Resource-Related Research (U24) applications for an Early Psychosis Intervention Network (EPINET) National Data Coordinating Center (ENDCC). The ENDCC will develop infrastructure to facilitate large-scale, practice-oriented research across clinics offering evidence-based Coordinated Specialty Care (CSC) to persons experiencing a first episode of psychosis. This NOFO focuses on research tools and resources directed at (1) optimizing the EPINET Core Assessment Battery (CAB) to support learning health care studies within and across CSC research networks; (2) adapting and implementing the CAB for use in publicly funded CSC programs that aspire to measurement-based care; (3) developing the informatics infrastructure and pipelines necessary to gather, store, and upload de-identified, person-level data collected across participating research networks to the NIMH Data Archive (NDA); and (4) assembling individual network datasets into a national repository of early psychosis clinical features, interventions, and treatment outcomes to be shared with qualified investigators via the NDA. In addition, the ENDCC will provide operational and technical support to the EPINET research consortium described in companion announcement RFA-MH-24-105.
This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn.
Applicants should carefully read the NOFO instructions and review the available PEDP guidance material.
Deadlines:
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Letter of Intent Due Date(s): February 29, 2024
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Application Due Date: March 29, 2024
RFA-MH-24-106 Expiration Date March 30, 2024
Direct costs are limited to no more than $1,000,000 in any one year.
The maximum project period is 5 years.