Engineering of Biomedical Systems

Funding Agency:
National Science Foundation

The Engineering of Biomedical Systems program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering program; and 4) the Disability and Rehabilitation Engineering program.

The goal of the Engineering of Biomedical Systems (EBMS) program is to provide opportunities for creating fundamental and transformative research projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term.  Projects are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. Projects must include objectives that advance both engineering and biomedical sciences.

Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term.

Full Proposal Accepted Anytime
 

Proposals submitted to other program announcements and solicitations, including the Faculty Early Career Development Program (CAREER), must meet their respective deadlines; please refer to the deadline dates specified in the appropriate announcement or solicitation. Proposals for EArly-concept Grants for Exploratory Research (EAGER) or Rapid Response Research (RAPID) can be submitted at any time but Principal Investigators must contact the cognizant program director prior to submission. Proposals for supplements or workshops can be submitted at any time, and PIs are encouraged to contact the cognizant PD prior to submission.

Agency Website

Areas of Interest

The EBMS program supports fundamental and transformative research in the following areas of biomedical engineering:

  • Development of validated models (living or computational) of healthy and pathological tissues and organ systems that can support improved fundamental understanding of these systems or development and testing of medical interventions,
  • Design and validation of systems that integrate living and non-living components for improved understanding, diagnosis, monitoring, and treatment of disease or injury,
  • Advanced biomanufacturing of three-dimensional tissues and organs, and
  • Design and subsequent application of technologies and tools, including those that leverage an organism’s microbiome, to investigate fundamental physiological and pathophysiological processes.

Innovative proposals outside of these specific areas of biomedical engineering may be considered. However, prior to submission, it is strongly recommended that the Principal Investigator contacts the program director to avoid the possibility of the proposal being returned without review. Related programs also fund biomedical engineering research, and PIs are encouraged to examine these to find the appropriate program for submission.

The long-term impact of the projects can be related to fundamental understanding of cell and tissue function in normal and pathological conditions, effective disease diagnosis and/or treatment, or improved health care delivery.

The EBMS program does not support proposals having as their central theme drug design and delivery, the development of biomedical devices that do not include a living biological component, or the development of animal models of disease. For consideration by the EBMS program, proposals that advance the design of tools or technologies should also apply those technologies to advance knowledge in biomedical science. NSF does not support clinical trials; however, feasibility studies involving human volunteers may be supported if appropriate to the project objectives.

Amount Description

The duration of unsolicited proposal awards in CBET is generally up to three years.  Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year (awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission.

 

Funding Type

Grant

Eligibility

Faculty

Category

Engineering and Physical Sciences
Environmental & Life Sciences
Interdisciplinary
Medical
Medical - Basic Science
Medical - Clinical Science
Medical - Translational